Sensitive and enzyme-free detection of epinephrine based on porous platinum nanoflowers assembling into multiwalled carbon nanotubes-graphene quantum dots hybrid modified electrode.

Haitao Liu, Junyi He, Yuqing Li, Bin Li, Jutao Zhou, Bowen Wu, Dan Li, Lixian Sun, Donghong Yu, Zhong Cao

Abstract read

In one paragraph

Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Haitao Liu *Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China.

Junyi He *Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China.

Yuqing LiHunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China.

Bin LiHunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China.

Jutao ZhouHunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China.

Bowen WuHunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China.

Dan LiHunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ld1004@126.com.

Lixian SunGuangxi Key Laboratory of Information Materials & Guangxi Collaborative Innovation Center for Structure and Properties for New Energy and Materials, School of Material Science and Engineering, Guilin University of Electronic Technology, Guilin, 541004, China.

Donghong YuDepartment of Chemistry and Bioscience, Aalborg University, 9220, Aalborg, Denmark.

Zhong CaoHunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation & Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Pharmaceutical Engineering, Changsha University of Science and Technology, Changsha, 410114, China. caoz@csust.edu.cn.

Funding

Guangxi Collaborative Innovation Centre of Structure and Property for New Energy and Materials, Science Research, Technology Development Project of Guilin 20210102-4National Natural Science Foundation of China 21545010, 21275022Natural Science Foundation of Hunan Province, China 2025JJ50092Postgraduate Scientific Research Innovation Project of Hunan Province CX20240800Scientific Research Fund of Hunan Provincial Education Department of China 24A0236, 24B0305

6 · The paper itself

Abstract

A kind of novel porous platinum nanoflowers (Pt NFs) was synthesized and assembled into acidified multiwalled carbon nanotubes (MWCNTs)-graphene quantum dots (GQDs) hybrid to form a ternary nanocomposite (Pt NFs/MWCNTs-GQDs), which was modified on surface of glassy carbon electrode (GCE). The morphology and structure of the nanocomposites were characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS), while the electrochemical behavior of epinephrine (EP) was investigated by means of cyclic voltammetry (CV) and differential pulse voltammetry (DPV). The fabricated Pt NFs/MWCNTs-GQDs/GCE demonstrated excellent electrocatalytic activity toward EP oxidation, with a good linear relationship between the peak currents and the concentrations of EP in the range 0.100 to 800 µM, and a detection limit of 14 nM (S/N = 3). In addition, the modified electrode presented good reproducibility, stability, and selectivity, which has been successfully used for determination of EP in medical injecta, as well as in porcine serum and urine samples with recoveries of 98.2% ~ 103.3% and 97.0% ~ 103.8%, respectively, showing that the proposed method is valuable in practical applications in medical analysis and disease diagnosis fields.

Indexed as

Electrochemical TechniquesEpinephrineGraphiteNanotubes, CarbonPlatinumQuantum DotsAnimalsElectrodesHumansLimit of DetectionPorosityReproducibility of ResultsSwineEpinephrineGraphiteNanotubes, CarbonPlatinumCarbon nanomaterialElectrochemical sensorEpinephrineMedical analysisModified glassy carbon electrodePorous platinum nanoflowers

Identifiers

PMID41201664

DOI10.1007/s00604-025-07645-5

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.