Evidence map›Paper›PMID 41201599›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Safety and efficacy of [

René Fernández, Cristian Soza-Ried, Vasko Kramer, Korbinian Krieger, Cristina Müller, Yun Qin, Frank Fliegert, Philipp Ritt, Konstantin Zhernosekov, Horacio Amaral and 2 more

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Tolerability of [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

René FernándezCenter for Nuclear Medicine & PET/CT PositronMed, Providencia, Santiago, 7501068, Chile. rfernandez@positronmed.cl.ORCID 0000-0002-0426-8536
Cristian Soza-RiedCenter for Nuclear Medicine & PET/CT PositronMed, Providencia, Santiago, 7501068, Chile.
Vasko KramerCenter for Nuclear Medicine & PET/CT PositronMed, Providencia, Santiago, 7501068, Chile.
Korbinian KriegerCenter for Radiopharmaceutical Sciences, PSI, Center for Life Sciences, Villigen-PSI, 5232, Switzerland.
Cristina MüllerCenter for Radiopharmaceutical Sciences, PSI, Center for Life Sciences, Villigen-PSI, 5232, Switzerland.
Yun QinITM Oncologics GmbH, Lichtenbergstrasse 1, Garching, Munich, 85748, Germany.
Frank FliegertITM Oncologics GmbH, Lichtenbergstrasse 1, Garching, Munich, 85748, Germany.
Philipp RittITM Oncologics GmbH, Lichtenbergstrasse 1, Garching, Munich, 85748, Germany.
Konstantin ZhernosekovITM Oncologics GmbH, Lichtenbergstrasse 1, Garching, Munich, 85748, Germany.
Horacio AmaralCenter for Nuclear Medicine & PET/CT PositronMed, Providencia, Santiago, 7501068, Chile.
Roberto EstayCenter for Nuclear Medicine & PET/CT PositronMed, Providencia, Santiago, 7501068, Chile.
Heinz NicolaiCenter for Nuclear Medicine & PET/CT PositronMed, Providencia, Santiago, 7501068, Chile.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProstate-specific membrane antigen (PSMA)-targeted radiopharmaceutical therapy (RPT) is a safe and well-tolerated treatment option for metastatic, castration-resistant prostate cancer (mCRPC). A new radioligand, comprising ibuprofen as an albumin-binding entity, [

methodsFrom July 2021 to January 2023 a total of seventeen eligible patients, sixteen (median age 71 years, range 63-83) were selected to receive up to four cycles of [

resultsSeven participants received 4 cycles of [

conclusionOverall survival and response rates of patients are consistent with previous reports on PSMA-targeted RPT while the absence of xerostomia can be considered an improvement. Up to four cycles of [

Indexed as

LutetiumProstatic Neoplasms, Castration-ResistantRadiopharmaceuticalsSafetyAgedAged, 80 and overDisease ProgressionHumansMaleMiddle AgedNeoplasm MetastasisProstate-Specific AntigenQuality of LifeRadioisotopesTreatment OutcomeLutetiumLutetium-177Prostate-Specific AntigenRadioisotopesRadiopharmaceuticals[177Lu]Lu-SibuDABEfficacyMCRPCProstate cancerRadiopharmaceutical therapySafety

Identifiers

PMID41201599
PMCPMC12920369

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.