Evidence map›Paper›PMID 41201540›Full record

ReviewDer Nervenarzt2025

[Update on tic disorders and Tourette syndrome].

Juan Carlos Baldermann, Selina Rolker, Kathrin Nickel, Katharina Domschke, Dominique Endres, Kirsten Müller-Vahl

Abstract readReviewEnglish Abstract
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juan Carlos BaldermannKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hauptstraße 5, 79104, Freiburg, Deutschland. juan.carlos.baldermann@uniklinik-freiburg.de.
Selina RolkerKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hauptstraße 5, 79104, Freiburg, Deutschland.
Kathrin NickelKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hauptstraße 5, 79104, Freiburg, Deutschland.
Katharina DomschkeKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hauptstraße 5, 79104, Freiburg, Deutschland.
Dominique EndresKlinik für Psychiatrie und Psychotherapie, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hauptstraße 5, 79104, Freiburg, Deutschland.
Kirsten Müller-VahlKlinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie, Medizinische Hochschule Hannover, Hannover, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tic disorders are neurodevelopmental disorders characterized by involuntary motor and/or vocal expressions (tics). According to ICD-10 and ICD-11 classifications they are differentiated into transient (≤ 12 months) and chronic (> 12 months) tic disorders; the diagnosis of Tourette syndrome requires the presence of multiple motor tics and at least one vocal tic persisting for more than 1 year. Typical features of tics include onset in childhood, a premonitory urge, at least partial suppressibility and a rostrocaudal distribution. Differential diagnoses include other hyperkinetic neurological disorders as well as obsessive-compulsive symptoms, stereotypes and functional tic-like behaviors, the latter often presenting with a late, abrupt onset and predominantly complex expressions. Behavioral therapy is considered the first-line treatment for clinically relevant tics. Pharmacological treatment includes off-label use of dopamine antagonists, such as aripiprazole. Comorbidities are common and require targeted comanagement.

Indexed as

Behavior TherapyTic DisordersTourette SyndromeChildCombined Modality TherapyDiagnosis, DifferentialDopamine AntagonistsEvidence-Based MedicineHumansTreatment OutcomeDopamine AntagonistsFunctional ticsMovement disorderNeurodevelopmental disordersReviewTics

Identifiers

PMID41201540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.