Evidence map›Paper›PMID 41201491›Full record

Observational studyNeuroradiology2026

Imaging features of otosclerosis on photon counting detector CT: a retrospective case series and literature review.

Dinesh Rao, John V Murray, Richard D Beegle, Jeet Patel, Mallory J Raymond, Joseph T Breen, Johnny Sandhu, Patricia A Rhyner

Abstract readReviewObservational Study
PubMed Publisher
In one paragraph

Observational study in Neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Photon-counting detector computed tomography for temporal bone: does higher resolution matter?Current opinion in otolaryngology & head and neck surgery · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dinesh RaoMayo Clinic, Jacksonville, United States. rao.dinesh@mayo.edu.
John V MurrayMayo Clinic, Jacksonville, United States.
Richard D BeegleMayo Clinic, Jacksonville, United States.
Jeet PatelMayo Clinic, Jacksonville, United States.
Mallory J RaymondMayo Clinic, Jacksonville, United States.
Joseph T BreenMayo Clinic, Jacksonville, United States.
Johnny SandhuMayo Clinic, Jacksonville, United States.
Patricia A RhynerMayo Clinic, Jacksonville, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeImaging findings of otosclerosis have been previously described using traditional energy integrated detector CT scanners. Recent developments in photon counting detector CT allow improved spatial and contrast resolution over previous technology.

methodsA retrospective observational case series review was carried out in 53 patients (106 temporal bones) who had imaging findings of otosclerosis. Imaging findings of otosclerosis were documented, including specific plaque location, the presence of otic capsule expansion, and IAC diverticula. The Symons and Fanning classification was used to categorize findings. The presence of the cochlear cleft was documented. 50 asymptomatic patients were reviewed to determine the presence of features that could be confounded for otosclerosis.

resultsPer the Symons and Fanning classification, the following types were found in individual temporal bones: type 0-13, type 1-48, type 2a - 12, type 2b - 6, type 2c - 16, type 3-4. Seven patients had imaging findings that did not fit the classification criteria, primarily isolated otospongiotic plaques in other parts of the otic capsule. The fissula ante fenestram was involved in 91 otosclerosis and 4 temporal bones in asymptomatic patients. The cochlear cleft was visible in 3 otosclerotic and 10 normal temporal bones. Otic capsule thickness in symptomatic patients: concave - 52, flat - 27, convex - 24. In asymptomatic patients: concave - 98, flat - 2, convex - 0. IAC diverticula: present in 36% of otosclerosis and 2% of normal. Isolated foci of otospongiosis were identified in several patients without classic fenestral or retrofenestral disease.

conclusionsPhoton counting CT allows excellent visualization of otospongiotic plaques. Due to the high resolution, subclinical findings can be overlooked in asymptomatic patients and plaque may be visualized in the otic capsule that are not part of existing classification systems. The current study coincides with previous studies which demonstrate that otosclerosis may occur in any part of the otic capsule.

Indexed as

OtosclerosisTomography, X-Ray ComputedAdolescentAdultAgedFemaleHumansMaleMiddle AgedPhotonsRetrospective StudiesTemporal BoneHearing lossOtic capsuleOtologyOtosclerosisOtospongiosisPhoton counting CT

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.