Evidence map›Paper›PMID 41201191›Full record

ArticleJournal of applied clinical medical physics2025

Effective spot size parameters for Acuros dose calculation algorithm using enhanced leaf modelling: Estimation based on small rectangular MLC fields.

Antonella Fogliata, Antonella Stravato, Marco Pelizzoli, Francesco La Fauci, Pasqualina Gallo, Andrea Bresolin, Luca Cozzi, Giacomo Reggiori

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Antonella FogliataRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.ORCID https://orcid.org/0000-0002-2282-9894
Antonella StravatoMedical Physics Department, A.O. San Giovanni-Addolorata, Roma, Italy.ORCID https://orcid.org/0000-0002-2001-7462
Marco PelizzoliRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.
Francesco La FauciRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.ORCID https://orcid.org/0000-0002-0023-4427
Pasqualina GalloRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.ORCID https://orcid.org/0000-0002-8959-3740
Andrea BresolinRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.
Luca CozziRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.
Giacomo ReggioriRadiotherapy and Radiosurgery Department, Humanitas Research Hospital IRCCS, Milan-Rozzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSmall field dosimetry plays a critical role in stereotactic radiotherapy, particularly for elongated fields shaped by multileaf collimators (MLCs). This study aims to optimize the Effective Spot Size (ESS) parameters in the Acuros dose calculation algorithm (Eclipse v18.0, with the enhanced leaf modelling ELM for MLC modelling) for accurate dose calculations of small, rectangular MLC-shaped fields. Measurements were based on the TRS-483 protocol and a recently proposed equivalent square field size determination method.

methodsField output factors (FOFs) were measured using a Varian TrueBeam linear accelerator with HD-MLC for 6 MV and 10 MV beams (both flattened and unflattened). Symmetric square and rectangular fields (0.5-4 cm sides) were shaped by the MLC, with jaws fixed at 4.4 × 4.4 cm

resultsThe optimized ESS parameters minimized FOF discrepancies between calculated and measured doses for elongated fields, improving calculation accuracy compared to vendor-recommended settings (ESSx = 0.5 mm, ESSy = 0.7 mm). Profiles and penumbra analyses supported these findings.

conclusionsELM in Eclipse v.18 improves MLC modelling by representing rounded leaf ends. Only ESS parameters remain user-tunable. A method to determine the ESS for the Acuros algorithm is presented, resulting in accurate algorithm configuration for elongated small fields shaped by an HD-MLC. Results are presented using 6 MV and 10 MV beams, both flattened and unflattened for an HD-MLC Varian. ESS affects output factors and penumbra, with dose calculations matching measurements within 0.2% ± 0.4% and a maximum difference of 1.1%.

Indexed as

AlgorithmsNeoplasmsParticle AcceleratorsPhantoms, ImagingRadiosurgeryRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedHumansRadiometryRadiotherapy DosageAcuroseffective spot sizeoutput factorsrectangular small fieldssmall fields

Identifiers

PMID41201191
PMCPMC12593538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.