Evidence map›Paper›PMID 41201185›Full record

ArticleJournal of applied clinical medical physics2025

Virtual 3D surface imaging system for the validation of tumor tracking algorithm used in surface-guided radiotherapy.

Xiaolong Wu, Ziwen Wei, Shaozhuang Zhai, Yang Zhang, Zhihua Liu, Tao Jiang, Lei Zhang, Junchao Qian

Abstract readValidation Study
In one paragraph

Article in Journal of applied clinical medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaolong WuSchool of Biomedical Engineering, Anhui Medical University, Hefei, China.
Ziwen WeiAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China.ORCID https://orcid.org/0009-0000-5954-3825
Shaozhuang ZhaiAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China.
Yang ZhangAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China.
Zhihua LiuAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China.
Tao JiangAnhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, P.R. China.
Lei ZhangInformation Materials and Intelligent Sensing Laboratory of Anhui Province, Anhui University, Hefei, P.R. China.
Junchao QianSchool of Biomedical Engineering, Anhui Medical University, Hefei, China.

Funding

Anhui Province Funds for Distinguished Young Scientists 2208085J10China Postdoctoral Science Foundation 2019M652403Collaborative Innovation Program of Hefei Science Center, CAS 2019HSC-CIP003National Natural Science Foundation of China 81871085National Natural Science Foundation of China 82271519National Natural Science Foundation of China U1932158Natural Science Foundation of Shandong Province ZR2019LZL018Project of Postdoctoral Innovation of Shandong Province 202002048
6 · The paper itself

Abstract

purposeTo develop a surface 3D reconstruction simulation system based on the Phase Measurement Profilometry (PMP) and the Unity physics engine and validate its feasibility for assisting in the development of the Surface-Guided Radiotherapy (SGRT) tumor tracking algorithm.

methodsThe components, such as cameras and projectors, are set up in the Unity environment to enable structured-light-based surface 3D reconstruction simulation using the PMP. This process includes structured light projection, camera calibration, phase unwrapping, and point cloud reconstruction procedures. The influence of parameter settings on the effectiveness of 3D reconstruction is investigated, including different distances and angles between the camera and the measurement surface, as well as variations in light intensity. The simulation capabilities of the system are validated by comparing surface imaging of the same human torso model in a radiotherapy room environment and within the simulation system. Additionally, the simulation system is further utilized to acquire surface imaging data required for the SGRT tumor tracking algorithm. A comparison is made between this data and the idealized skin surface imaging data obtained directly from CT reconstruction segmentation to verify the system's supportive role in the development of the SGRT tumor tracking algorithm.

resultsThe effects of varying light intensity and object positioning in the simulation system are consistent with those reported in previous studies conducted in real-world environments. The root mean square errors (RMSE) of the surface imaging point clouds from different perspectives between the simulation system and the actual environment are 0.46, 0.47, and 0.52 mm, all at sub-millimeter levels. The validation in the development of the SGRT tumor tracking algorithm indicates that the simulation system enables the SGRT algorithm development to avoid relying on overly idealized surface imaging data.

conclusionsThe simulation system based on PMP and Unity has been proposed, enabling a broader range of measurement conditions to be set in the virtual environment, thereby saving costs for measurements in real-world scenarios. This system can also be utilized to assist in the validation of the SGRT tumor tracking algorithms, thereby advancing progress in this field.

Indexed as

AlgorithmsImage Processing, Computer-AssistedImaging, Three-DimensionalNeoplasmsPhantoms, ImagingRadiotherapy, Image-GuidedRadiotherapy Planning, Computer-AssistedComputer SimulationHumansRadiotherapy DosageRadiotherapy, Intensity-ModulatedTomography, X-Ray Computedphase measurement profilometrysurface‐guided radiotherapysurface imagingunityvirtual simulation

Identifiers

PMID41201185
PMCPMC12593527

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.