Evidence map›Paper›PMID 41201148›Full record

ArticleRevista de neurologia2025

Endovascular Therapy for Acute Basilar Artery Occlusion: Prognosis Prediction Value from Clinical to Imaging Variables.

Shunyang Chen, Yiying Pan, Pengjun Chen, Chenchen Hong, Tian Gao, Chaoming Huang, Jiansong Ji

Abstract read
In one paragraph

Article in Revista de neurologia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shunyang ChenDepartment of Radiology, Lishui Central Hospital, Shaoxing University, 312000 Shaoxing, Zhejiang, China.
Yiying PanDepartment of Radiology, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, 310022 Hangzhou, Zhejiang, China.
Pengjun ChenZhejiang Provincial Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, 323000 Lishui, Zhejiang, China.
Chenchen HongZhejiang Provincial Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, 323000 Lishui, Zhejiang, China.
Tian GaoZhejiang Provincial Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, 323000 Lishui, Zhejiang, China.
Chaoming HuangZhejiang Provincial Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, 323000 Lishui, Zhejiang, China.
Jiansong JiZhejiang Provincial Key Laboratory of Imaging Diagnosis and Minimally Invasive Intervention Research, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui Hospital of Zhejiang University, 323000 Lishui, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute basilar artery occlusion (BAO) correlates with high risks of disability and mortality, and the best imaging and treatment strategies for BAO remain controversial. This study evaluated the association between baseline imaging, clinical variables, and clinical outcomes of patients with BAO undergoing endovascular therapy (EVT).

methodsData from 75 patients with BAO who had EVT at a single center were retrospectively analyzed. Baseline National Institutes of Health Stroke Scale (NIHSS) scores, clinical baseline data, and various known scores and perfusion deficit volumes on non-contrast computed tomography (NCCT), CT angiography source images (CTA-SI), and CT perfusion (CTP) were collected to explore effective predictive factors for prognosis. The functional outcome of the analysis was satisfactory (90-day modified Rankin Scale score ≤3). Predictors of functional outcomes were assessed through receiver operating characteristic analyses and binary logistic regression.

resultsAmong the 75 patients who fulfilled the inclusion criteria, 29 achieved a good outcome (39%) and 46 (61%) achieved a poor outcome. The Critical Area Perfusion Score (CAPS), pons midbrain index (PMI), time to maximum (Tmax) >6 s, Tmax >10 s, and reduction in CBF compared with normal brain tissue (rCBF) <30%, cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT) Posterior Circulation Alberta Stroke Program Early CT Score (pc-ASPECTS) were independent predictors of favorable prognosis. The CAPS was the best predictor of good clinical outcomes, with an area under the curve of 0.862 (95% confidence interval [CI], 0.772-0.952). Combined diagnosis with the baseline NIHSS score improved the prognosis prediction accuracy.

conclusionsIn patients with stroke that resulted in BAO after EVT, CAPS, PMI, Tmax >6 s, Tmax >10 s, rCBF <30% volume, and CBV pc-ASPECTS were excellent predictors of higher risk of disability and mortality. Furthermore, CAPS had the best accuracy, and overall predictive value could be improved when combined with the baseline NIHSS score for diagnosis.

Indexed as

Arterial Occlusive DiseasesEndovascular ProceduresVertebrobasilar InsufficiencyAcute DiseaseAgedAged, 80 and overBasilar ArteryComputed Tomography AngiographyFemaleHumansMaleMiddle AgedPredictive Value of TestsPrognosisRetrospective StudiesTreatment Outcomebasilar artery occlusionendovascular therapyprognosisstroke

Identifiers

PMID41201148
PMCPMC12593746

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.