ReviewChemistryOpen2026
Microwave-Assisted Organic Syntheses in Deep Eutectic Solvents: A Win-Win Association for Sustainable Chemistry.
Review in ChemistryOpen, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- A Comprehensive Review of Recent Advances in Sustainable Synthesis of Bio-Based Furanic Compounds Via Chemical, Biological, Chemobiological and Other Combination Approach in Benign Systems.Applied biochemistry and biotechnology · 2026Review
- Synthesis of Fluoroquinolones: Revisiting the Grohe Route in DES-Based Media.Pharmaceuticals (Basel, Switzerland) · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 12 principles of green chemistry guide the scientific community toward the development of chemical processes that are more respectful of the environment and safer for human health. In organic synthesis, this mainly involves the use of sustainable alternatives to conventional organic solvents, energy-efficient processes, and waste minimization. In this context, this review focuses on the use of deep eutectic solvents (DES) in microwave-assisted organic synthesis. Indeed, DES, due to their nonvolatility, nonflammability, and low toxicity compared to conventional organic solvents, are considered desirable "green solvents" for the development of environmentally friendly processes. Moreover, their physicochemical properties make them ideal media for microwave heating. Thus, all organic syntheses using DES as solvent and microwave heating documented in the literature are reported, including heterocycle synthesis, nitrogen quaternization reactions, 5-hydroxymethylfurfural production, Knoevenagel reactions, and miscellaneous transformations. The recyclability of DES-based systems and their scalability, where applicable, are reported. Mechanistical considerations when DES are involved are also described. Compared with conventional heating methods, microwave heating of DES media generally results in good yields and a significant reduction in reaction times. This DES-MW combination appears promising for more sustainable organic syntheses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.