Analysis of the main components of LSPN based on broadly targeted metabolomics technology.

Feng Qin, Yuyong Chen, Dada Wang, Jingui Li, Shanyuan Zhu

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Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

5 authors.

Feng QinJiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Engineering Technology Research Center for Modern Animal Science and Novel Veterinary Pharmaceutic Development, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, Jiangsu, China.

Yuyong ChenCollege of Food Science and Technology, Jiangsu Agri-animal Husbandry Vocational College, Taizhou, Jiangsu, China.

Dada WangCollege of Animal Pharmaceutical, Jiangsu Agri-animal Husbandry Vocational College, Taizhou, Jiangsu, China.

Jingui LiCollege of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu, China.

Shanyuan ZhuJiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Engineering Technology Research Center for Modern Animal Science and Novel Veterinary Pharmaceutic Development, Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to (1) establish a broadly targeted metabolomics workflow to evaluate batch-to-batch variability in Methods: Our hypothesis was that thermal extraction parameters would significantly alter saponin profiles, detectable via orthogonal metabolomic approaches (HPLC-MS/MS, PCA). Results: The results showed a strong positive correlation (pearson correlation coefficient >0.92) between triterpenoid saponins in LSPN-S and LSPN-C. Thirty-eight triterpenoid saponins were detected, of which 11 were up-regulated, 5 were down-regulated, and the other 22 had less than a two-fold difference in content. Ginsenoside Rb3 showed a modest but significant downregulation in LSPN-S (fold change = 0.45, VIP = 1.11) compared with LSPN-C. Discussion: Metabolomic analysis confirmed the suitability of the selected

Indexed as

biological activitymain componentsPanax notoginseng stems and leavestargeted metabolometriterpenoid saponins

Identifiers

PMID41200492

DOI10.3389/fpls.2025.1618168

PMCPMC12587676

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.