Evidence map›Paper›PMID 41200464›Full record

ArticleCase reports in radiology2025

PSMA PET/CT Incidental Detection of Tumor Thrombus From Unsuspected Renal Cell Carcinoma and Comparison with FDG PET/CT.

William Y Raynor, Stephen J Sozio, Anthony Yudd, Tina Mayer, Jeffrey S Kempf

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In one paragraph

Article in Case reports in radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William Y RaynorDepartment of Radiology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0000-0002-4558-6805
Stephen J SozioDepartment of Radiology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Anthony YuddDepartment of Radiology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Tina MayerDivision of Medical Oncology, Department of Medicine, Rutgers Cancer Institute, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
Jeffrey S KempfDepartment of Radiology, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.ORCID https://orcid.org/0009-0005-3575-8035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell renal cell carcinoma (ccRCC) is typically prostate-specific membrane antigen (PSMA)-avid, likely related to PSMA expression in the tumor neovasculature, suggesting a potential role for evaluation by PSMA PET/CT. We describe a 77-year-old patient with prostate cancer who was incidentally found to have ccRCC on imaging with PSMA PET/CT, with subsequent staging by FDG PET/CT. He was diagnosed with prostate cancer 17 years prior and treated with radical prostatectomy and radiation therapy within a year of diagnosis. Biochemical recurrence with PSA of 1.0 ng/mL prompted imaging with PSMA PET/CT, which showed an unexpected finding of abnormal uptake within the right renal vein and inferior vena cava (IVC), suggesting possible tumor thrombus (SUVmax 8.8), with mild uptake corresponding to a suspected right renal mass. In addition, there was a PSMA-avid right paratracheal nodal metastasis measuring 3.3 cm (SUVmax 8.4). Subsequent FDG PET/CT again showed the renal mass, tumor thrombus (SUVmax 3.6), and only low-level uptake in the right paratracheal mass (SUVmax 2.3). Right nephrectomy was performed, confirming the presence of ccRCC in the right kidney with tumor thrombus extending to the right renal vein and IVC. FDG PET/CT restaging showed no recurrence in the nephrectomy bed and a stable FDG-avid right paratracheal mass. After stereotactic body radiation therapy (SBRT) directed to the right paratracheal mass, follow-up PSMA PET/CT showed decreased uptake (SUVmax 4.8), suggesting its usefulness for detecting and monitoring ccRCC.

Indexed as

18F-DCFPyL18F-fluorodeoxyglucosepositron emission tomographyPSAradioligand therapyRCC

Identifiers

PMID41200464
PMCPMC12588747

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