ArticleFrontiers in neurology2025
Preoperative sleep disturbance as a risk factor for moderate-to-severe postoperative pain in hemifacial spasm patients: a prospective cohort study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: This study aims to examine the impact of preoperative sleep disturbances on postoperative pain levels among individuals undergoing hemifacial spasm (HFS) surgery. The findings will establish a theoretical foundation for developing targeted interventions to ameliorate postoperative pain management in this patient population. Methods: Hemifacial spasm patients who were treated and operated on at Peking University People's Hospital from October 2023 to February 2024 were selected as participants via convenience sampling. Sleep quality was quantitatively assessed using the Pittsburgh Sleep Quality Index (PSQI), while postoperative pain severity was measured with the Numerical Rating Scale (NRS). Perioperative clinical data were systematically recorded at postoperative day 1, 3, and 7 (POD 1, 3, and 7). Univariate and multivariate regression analyses were subsequently conducted to identify predictors of moderate-to-severe pain persisting at the 1-week postoperative timepoint. Results: A cohort of 120 patients diagnosed with hemifacial spasm participated in this study. Based on preoperative Pittsburgh Sleep Quality Index (PSQI) scores, participants were stratified into two groups: a low-sleep-quality group (PSQI ≥ 7, Conclusion: Preoperative sleep disturbances elevate the risk of patients with hemifacial spasm experiencing moderate-to-severe pain postoperatively. Therefore, proactive management of sleep disturbances prior to surgery represents a valuable strategy for enhancing postoperative analgesia in this patient population. However, the generalizability of these findings is limited to HFS patients undergoing MVD, and further validation in broader surgical cohorts is warranted.
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