Evidence map›Paper›PMID 41200408›Full record

ArticleEuropean journal of cancer care2025

Physical and Psychological Burdens Among Breast Cancer Survivors: Evaluating Post-Treatment Gait Impairment, Falls, and Depression Using Real-World Data.

Asmaa Namoos, Nicholas Thomson, Carol Olson, Vanessa Sheppard, Michel Aboutanos

Abstract read
In one paragraph

Article in European journal of cancer care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Asmaa NamoosDepartment of Surgery, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-7720-0500
Nicholas ThomsonDepartment of Surgery, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-5127-8174
Carol OlsonDepartment of Surgery, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-0759-9445
Vanessa SheppardDepartment of Social and Behavioral Sciences, School of Public Health, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0003-2874-6659
Michel AboutanosDepartment of Surgery, School of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0003-2090-1992

Funding

Wright Regional Center for Clinical and Translational ScienceUM1TR004360 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI FREDERICK Gerard MOELLER · 2023 to 2026
$16.3M
NCATS NIH HHS UM1 TR004360
6 · The paper itself

Abstract

Background: Breast cancer survivors face a dual burden of physical and psychological challenges, which may persist long after treatment. This study aims to evaluate the physical impairments and psychological outcomes among breast cancer survivors compared to individuals without breast cancer. Methods: We conducted a retrospective cohort study using data from 3650 breast cancer survivors and 145,280 individuals without breast cancer from the Virginia Commonwealth University Health System (VCUHS) between January 2024 and 2025. Data were extracted through the TriNetX platform using ICD-10 codes to identify relevant diagnoses and outcomes. Physical outcomes included abnormalities of gait and mobility, unsteadiness on feet, and falls. Psychological outcomes assessed were depression, stress-related disorders, and anxiety following falls. Risk differences, risk ratios (RR), and odds ratios with 95% confidence intervals (CIs) were calculated to compare outcomes between groups. Results: Breast cancer survivors exhibited a higher risk of physical impairments compared to nonbreast cancer individuals. The risk of gait and mobility abnormalities was 2.725% in breast cancer survivors versus 1.741% in the comparison group (RR: 1.565; 95% CI: 1.285-1.906; Conclusion: Functional limitations such as unsteadiness and falls are significantly more common among breast cancer survivors and are strongly associated with psychological distress. These findings support mobility impairments as a potential pathway linking cancer treatment to adverse mental health outcomes. Future research should integrate structured ICD-10 data with unstructured oncology notes to enhance fall prediction models and guide personalized survivorship care.

Indexed as

anxietybreast cancer survivorsdepressionfallsgait abnormalitiesmobility impairmentphysical impairmentpsychological distressstress-related disorderssurvivorship care

Identifiers

PMID41200408
PMCPMC12588077

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.