Evidence map›Paper›PMID 41200383›Full record

ArticleFASEB bioAdvances2025

Impact of Type 1 Diabetes on Endothelial Cells Derived From Living Donors.

Isra Marei, Maria Vinokurova, Li Qiucheng, Lasse Nyhegn, Eric Dubuis, Anam Baig, Nura Mohamed, Stephen Rothery, Nicholas S Kirkby, Victoria Salem and 3 more

Abstract read
In one paragraph

Article in FASEB bioAdvances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Metabolic dysfunction and the use of adjunct medications in type 1 diabetes.Current opinion in endocrinology, diabetes, and obesity · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Isra MareiNational Heart and Lung Institute Imperial College London London UK.
Maria VinokurovaNational Heart and Lung Institute Imperial College London London UK.
Li QiuchengNational Heart and Lung Institute Imperial College London London UK.
Lasse NyhegnNational Heart and Lung Institute Imperial College London London UK.
Eric DubuisNational Heart and Lung Institute Imperial College London London UK.
Anam BaigNational Heart and Lung Institute Imperial College London London UK.
Nura MohamedNational Heart and Lung Institute Imperial College London London UK.
Stephen RotheryNational Heart and Lung Institute Imperial College London London UK.
Nicholas S KirkbyNational Heart and Lung Institute Imperial College London London UK.
Victoria SalemDepartment of Bioengineering Imperial College London London UK.
Nicholas OliverDepartment of Metabolism, Digestion and Reproduction Imperial College London London UK.
Jane A MitchellNational Heart and Lung Institute Imperial College London London UK.
Blerina Ahmetaj-ShalaNational Heart and Lung Institute Imperial College London London UK.ORCID https://orcid.org/0000-0003-4488-7689

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelial colony forming cells (ECFCs) derived from peripheral blood have been shown to retain disease phenotype in several conditions thus possessing great translational potential for regenerative medicine. Hyperglycaemia may alter the phenotype of ECFCs yet the characteristics of ECFCs isolated from people with type 1 diabetes (T1D) have not been described. Here, we establish whether ECFCs can be successfully isolated from donors with T1D and we characterize their functional properties. Human ECFCs were isolated from peripheral blood of up to 9 control and T1D donors. Expression of cell markers and cytokines was analyzed using immunocytochemistry, RT-PCR and ELISA. Ca

Indexed as

cardiovascular pathogenesisendothelial cellsinflammationregenerative medicinetype 1 diabetesvascular leak

Identifiers

PMID41200383
PMCPMC12587046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.