Evidence map›Paper›PMID 41200347›Full record

ArticleOpen veterinary journal2025

Evaluation of serum levels of CRP and TNF-α in dogs infected with

Krasimira Gospodinova, Koycho Koev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Krasimira GospodinovaDepartment of General and Clinical Pathology, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria.
Koycho KoevDepartment of Veterinary Microbiology, Infectious and Parasitic Diseases, Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Canine monocytic ehrlichiosis (CME) and canine granulocytic anaplasmosis (CGA), caused by Aim: This study aimed to compare serum CRP and TNF-α in CME, CGA, and co-infected dogs and assess their relationships with hematological, biochemical, and liver enzyme changes. Methods: In 134 dogs showing clinical signs of CME/CGA, infections were confirmed using SNAP Results: Of the dogs tested, 112 (83.6%) were seropositive and 77 (68.8%) were PCR-positive ( Conclusion: CRP and TNF-α are valuable indicators of systemic inflammation in CME and CGA, with maximal increases and stronger links to liver injury in co-infections, supporting their use in diagnosis and prognosis.

Indexed as

AnaplasmosisC-Reactive ProteinDog DiseasesEhrlichiosisTumor Necrosis Factor-alphaAnaplasma phagocytophilumAnimalsBiomarkersCoinfectionDogsEhrlichia canisFemaleMaleBiomarkersC-Reactive ProteinTumor Necrosis Factor-alphaAnaplasma phagocytophilumCo-infectionCRPDogsEhrlichia canisTNF-α

Identifiers

PMID41200347
PMCPMC12587954

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.