ArticleOpen veterinary journal2025
Distribution of androgen receptor immunoreactive cells in the adrenal glands of
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: The adrenal glands play a vital role in regulating endocrine functions by producing corticosteroids, mineralocorticoids, and androgens. Adrenal androgens contribute to overall systemic androgen levels, primarily through interactions with androgen receptors (ARs) within the gland. Although the distribution of AR has been studied in various mammalian species, no research has yet focused on the Sunda porcupines ( Aim: This study aimed to investigate the endocrinal regulation of the adrenal gland of Sunda porcupines Methods: This study was conducted at the Laboratory of Anatomy, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Indonesia, from January to August 2022. The research involved six adrenal glands sourced from Sunda porcupines ( Results: AR-IR cells were predominantly localized in the ZG, with a smaller presence observed in the ZF of the adrenal cortex. No AR expression was detected in the ZR. Interestingly, AR-IR cells were also detected in the adrenal medulla. Conclusion: This study indicates species-specific distribution patterns of AR-IR cells, which may clarify the role of ARs in physiological adaptation of Sunda porcupines (
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