Evidence map›Paper›PMID 41200228›Full record

ArticleFrontiers in psychiatry2025

Acute hepatitis B virus infection in pregnancy: a case report of three patients with comorbid anxiety and their clinical outcomes.

Shenlu Wu, Kejie Hu, Yufang Wang

Abstract readCase Reports
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shenlu WuThe Second School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
Kejie HuDepartment of Gastroenterology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, China.
Yufang WangDepartment of Gastroenterology, Hangzhou Third People's Hospital, Hangzhou, Zhejiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case series reports three pregnant women with acute hepatitis B virus (AHB) infection, exploring their clinical outcomes and comorbid anxiety. All three patients presented with abnormal liver function and positive HBV markers. They received supportive therapy (liver-protective, enzyme-lowering agents, etc.), achieving HBsAg clearance and virological cure, with normal liver function during follow-up (one patient lost to follow-up). Despite favorable biomedical outcomes, all experienced significant anxiety over maternal-fetal health and disease progression. This study emphasizes that AHB in pregnancy, though usually self-limited, requires integrating psychosocial support into multidisciplinary management to address perinatal mental health, supporting WHO's 2030 viral hepatitis elimination goal.

Indexed as

acute hepatitis Bcase reportearly gestationperinatal mental healthvirological clearance

Identifiers

PMID41200228
PMCPMC12586072

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.