Evidence map›Paper›PMID 41200073›Full record

ArticleThe Journal of innovations in cardiac rhythm management2025

Impact of Coronavirus Disease 2019 on Sick Sinus Syndrome: Trends in Incidence and Pacemaker Implantation.

Dharmindra Dulal, Ahmed Maraey, Blair Grubb

Abstract read
In one paragraph

Article in The Journal of innovations in cardiac rhythm management, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Letter from the Editor in Chief.The Journal of innovations in cardiac rhythm management · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dharmindra DulalDepartment of Internal Medicine, Ohio State University Wexner Medical Center, Columbus, Toledo, OH, USA.
Ahmed MaraeyDivision of Cardiovascular Medicine, University of Toledo Medical Center, Toledo, OH, USA.
Blair GrubbDivision of Cardiovascular Medicine, University of Toledo Medical Center, Toledo, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sick sinus syndrome (SSS) is a cardiac conduction disorder that often necessitates pacemaker implantation, especially in older adults. Emerging evidence suggests a potential association between coronavirus disease 2019 (COVID-19) infection and SSS, but the impact on SSS trends and permanent pacemaker (PPM) implantation rates remains unclear. This study compares the pre- and post-COVID-19 trends in SSS incidence and PPM implantation rates. Using the TriNetX Research Network, we analyzed the monthly incidence rate (IR) of SSS and the rate of PPM implantation in the overall population from January 2018 to December 2023. Additionally, we conducted a subgroup analysis focusing on patients >50 years of age to examine trends in IR and PPM implantations during the same period. To evaluate changes before and after COVID-19, we used interrupted time series analysis, with March 1, 2020, as the cutoff. In the overall SSS population, the IR increased significantly post-COVID-19 (IR, 1.80 cases/100,000 person-years [PY] per month;

Indexed as

COVID-19incidence ratepacemaker implantationsick sinus syndrome

Identifiers

PMID41200073
PMCPMC12588589

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.