Evidence map›Paper›PMID 41200014›Full record

ReviewThe Lancet regional health. Europe2025

Mental health disorders and their impact on cardiovascular health disparities.

Viola Vaccarino, Eva Prescott, Amit J Shah, J Douglas Bremner, Paolo Raggi, Olivija Dobiliene, Chris P Gale, Raffaele Bugiardini

Abstract readReview
In one paragraph

Review in The Lancet regional health. Europe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  16. Equity and cardiovascular disease: time to take it seriously.The Lancet regional health. Europe · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Viola VaccarinoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
Eva PrescottCenter for Cardiovascular Research, Bispebjerg Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.
Amit J ShahDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, USA.
J Douglas BremnerDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, USA.
Paolo RaggiMazankowski Alberta Heart Institute, University of Alberta, Edmonton, Alberta, Canada.
Olivija DobilieneHospital of Lithuanian University of Health Sciences, Lithuania.
Chris P GaleLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Raffaele BugiardiniDepartment of Medical and Surgical Sciences, University of Bologna, Italy.

Funding

Vascular Responses During Mental StressP01HL101398 · NHLBI · EMORY UNIVERSITY · PI QUYYUMI, ARSHED A · 2010 to 2015
$11.0M
Mental Stress and Myocardial Ischemia after MI: Sex Differences, Mechanisms and PrognosisR01HL109413 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2012 to 2023
$6.9M
PTSD and Ischemic Heart Disease Progression: A Longitudinal Twin StudyR01HL125246 · NHLBI · EMORY UNIVERSITY · PI VACCARINO, VIOLA · 2015 to 2018
$3.4M
NHLBI NIH HHS P01 HL101398NHLBI NIH HHS R01 HL109413NHLBI NIH HHS R01 HL125246
6 · The paper itself

Abstract

Mental health disorders are highly prevalent and are associated with significant morbidity, disability, and reduced life expectancy. A key contributor to this disparity is the increased risk of cardiovascular disease (CVD), which is partially driven by inequalities in social determinants of health, healthcare access, and quality of care. To address this challenge, The Lancet Regional Health-Europe convened experts to evaluate the current state of knowledge on inequalities and disparities in cardiovascular health among people with mental health disorders and propose recommendations to address these disparities. This Series paper aims to raise awareness of the disparities in CVD and health-care quality faced by individuals with common mental health conditions such as major depression, anxiety disorders, schizophrenia, bipolar disorder, and posttraumatic stress disorder. There is an urgent need for increased investment, intervention, and research to address the burden of CVD in these populations. Effective management of the comorbidity between mental health disorders and CVD requires an integrated and holistic approach to clinical care that addresses shared risk factors and the complex interactions between physical and mental health.

Indexed as

Cardiovascular diseaseEpidemiologyHealth inequalitiesMental healthPsychiatric disordersPublic health

Identifiers

PMID41200014
PMCPMC12587323

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.