Evidence map›Paper›PMID 41200013›Full record

ReviewThe Lancet regional health. Europe2025

Challenges in the prevention, treatment and management of cardiovascular disease among older adults.

Nick Townsend, Adam Timmis, Andrejs Erglis, Davor Miličić, Pasquale Perrone-Filardi, Franz Weidinger, Tomasz Guzik, Chris P Gale

Abstract readReview
In one paragraph

Review in The Lancet regional health. Europe, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  12. Equity and cardiovascular disease: time to take it seriously.The Lancet regional health. Europe · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Nick TownsendSchool for Policy Studies, University of Bristol, UK.
Adam TimmisEuropean Heart Agency, European Society of Cardiology, Brussels, Belgium.
Andrejs ErglisUniversity of Latvia, Pauls Stradins Clinical University Hospital, Latvia.
Davor MiličićUniversity of Zagreb, School of Medicine, Croatia.
Pasquale Perrone-FilardiDepartment of Advanced Biomedical Sciences, Federico II University of Naples, Italy.
Franz WeidingerKlinik Landstrasse, Vienna Healthcare Group, Vienne, Austria.
Tomasz GuzikCentre for Cardiovascular Sciences, Queen's Medical Research Institute, University of Edinburgh, UK.
Chris P GaleDepartment of Cardiology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ageing population in Europe is contributing to a growing proportion of older people affected by cardiovascular disease (CVD). Older adults account for most of the CVD burden and face unique challenges, complicated by age-related physiological changes and comorbidities. Older patients are underrepresented in clinical trials, leading to scientific and clinical equipoise, and inequities in care. Managing CVD in this age group is complex. Despite the availability of guideline-directed therapies, older adults often do not receive optimal treatment due to the complexity of their conditions and are at higher risk of complications. Strategies for the treatment and management of CVD in older individuals should be driven by patient centred outcomes relating to functional capacity and quality of life. Social and economic factors, such as financial limitations and isolation, further exacerbate age-related CVD inequalities and highlight the need for a holistic approach to care. To address this challenge, The Lancet Regional Health-Europe convened experts to evaluate the current state of knowledge on inequalities and disparities in cardiovascular health among older adults and propose recommendations to address these disparities. This Series paper aims to explore inequalities in, and the escalating burden of, CVD for older adults, with a focus on treatment, prevention, and strategies to support their physical and mental well-being.

Indexed as

Cardiovascular diseaseElderlyInequalities

Identifiers

PMID41200013
PMCPMC12587328

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.