ArticleAnnals of gastroenterological surgery2025
Prognostic Impact of Hepatectomy Versus Radiofrequency Ablation for Non-Small Hepatocellular Carcinoma (2-3 cm): A Case-Matched Study.
Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Clinical-pathological characteristics and prognosis of elderly primary liver cancer patients.American journal of cancer research · 2026Article
- Letter to Editor Regarding "Prognostic Impact of Hepatectomy Versus Radiofrequency Ablation for Non-Small Hepatocellular Carcinoma (2-3 Cm): A Case-Matched Study".Annals of gastroenterological surgery · 2025Article
Corrections and comments
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Authors and funding
9 authors.
Funding
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Abstract
Background: While the surgery versus radiofrequency ablation (RFA) (SURF) trial demonstrated no significant difference in long-term outcomes between hepatectomy and RFA for patients with small hepatocellular carcinomas (HCCs) (≤ 3 cm and less than three nodules), uncertainty persists regarding the potential risk of local recurrence and inferior overall survival (OS) associated with RFA for HCCs with a diameter ≥ 2 cm when compared to hepatectomy. This study aimed to elucidate the prognostic outcomes of hepatectomy versus RFA for treating primary HCC of 2-3 cm and less than three nodules. Methods: This retrospective study included 398 patients with primary HCC measuring 2-3 cm and having less than three nodules. Propensity score matching (PSM) was employed to balance the hepatectomy ( Results: Before PSM, hepatectomy showed better RFS (hazard ratio [HR] = 0.57, Conclusion: For patients with primary HCC measuring 2-3 cm and having less than three nodules, hepatectomy may offer superior prognostic benefits, particularly in those with elevated AFP levels. These findings emphasize the importance of individualized treatment decisions based on tumor size and AFP levels.
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