ArticleAnnals of gastroenterological surgery2025
Prognostic Value of Serum Insulin-Like Growth Factor-1 in Patients With Anal Fistula Treated by Incision-Thread-Drawing Surgery.
Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Anal fistula is a chronic condition characterized by an abnormal tract between the anal canal and perianal skin, often leading to infection, inflammation, and impaired quality of life. Incision-thread-drawing surgery is the main treatment for anal fistula. However, the risk of poor postoperative healing remains significant. This study investigates the prognostic value of preoperative serum insulin-like growth factor-1 (IGF-1) levels in predicting wound healing after incision-thread-drawing surgery for anal fistula. Methods: A total of 129 patients undergoing incision-thread-drawing surgery for anal fistula were enrolled. Patients were divided into a healing group ( Results: Preoperative serum IGF-1 levels were significantly lower in the non-healing group ( Conclusion: Preoperative serum IGF-1 levels are a valuable prognostic biomarker for predicting wound healing and postoperative recovery in patients undergoing incision-thread-drawing surgery for anal fistula, potentially guiding clinical decision-making and patient management strategies.
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