ArticleAnnals of gastroenterological surgery2025
Patient-Reported Outcomes and Surgical Results of Hand-Sewn Versus Stapled Anastomosis for Lower Rectal Cancer Located 4-5 cm From the Anal Verge: A Subanalysis of the Ultimate Study.
Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sexual dysfunction outcomes and reporting disparities after multimodal treatment for rectal cancer: A systematic review and narrative synthesis.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Pooled it
- Essential Updates 2024-2026: Advances in Colorectal Cancer Surgery.Annals of gastroenterological surgery · 2026Review
Corrections and comments
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Authors and funding
30 authors.
Funding
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Abstract
Background: Preserving anorectal function while achieving oncological success is crucial in the treatment of lower rectal cancer near the anal canal. Despite advancements in laparoscopic surgery that facilitate anal preservation, post-operative anorectal dysfunction considerably affects quality of life. Both hand-sewn and stapled anastomoses are suitable options for tumors located 4-5 cm from the anus. However, evidence comparing the functional outcomes and complications associated with both anastomosis methods is lacking. Methods: This multicenter, single-arm prospective study included patients with cT1-T2/N0/M0 adenocarcinoma located 4-5 cm from the anal verge, scheduled for upfront laparoscopic surgery. Anorectal function, post-operative complications, urinary and male sexual function, and oncological outcomes were assessed using the validated scores. Results: A total of 135 patients were analyzed and divided into hand-sewn ( Conclusion: Stapled anastomosis may provide better anorectal function with comparable safety and oncological outcomes to hand-sewn anastomosis. Therefore, stapled anastomosis may be preferred for tumors located 4-5 cm from the anal verge to ensure oncological safety. Trial Registration: This study was registered in the UMIN Clinical Trials Registry System (UMIN 000011750).
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