Evidence map›Paper›PMID 41199588›Full record

ReviewThe New phytologist2026

Transcriptional outputs and condensates - formation and function.

Stephanie Hutin, Jiawei Li, Mark D Tully, Xuelei Lai, Chloe Zubieta

Abstract readReview
In one paragraph

Review in The New phytologist, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephanie HutinLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble-Alpes, CNRS, CEA, INRAE, IRIG-DBSCI, 17 rue des Martyrs, 38000, Grenoble, France.ORCID https://orcid.org/0000-0002-2168-5841
Jiawei LiNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, 430070, China.ORCID https://orcid.org/0009-0003-1144-124X
Mark D TullyStructural Biology, European Synchrotron Radiation Facility, 71 Avenue des Martyrs, 38000, Grenoble, France.ORCID https://orcid.org/0000-0001-5450-9900
Xuelei LaiNational Key Laboratory of Crop Genetic Improvement, Hubei Hongshan Laboratory, Huazhong Agricultural University, Wuhan, 430070, China.ORCID https://orcid.org/0000-0003-4989-2444
Chloe ZubietaLaboratoire de Physiologie Cellulaire et Végétale, Université Grenoble-Alpes, CNRS, CEA, INRAE, IRIG-DBSCI, 17 rue des Martyrs, 38000, Grenoble, France.ORCID https://orcid.org/0000-0003-4558-9333

Funding

Agence Nationale de la Recherche ANR-17-EURE-0003Agence Nationale de la Recherche ANR-21-CE11-0037Agence Nationale de la Recherche ANR-23-CE20-0019Campus FranceNational Natural Science Foundation of China 32270303
6 · The paper itself

Abstract

The dynamic spatiotemporal organization of macromolecules is key to the proper function of the cell, allowing the exquisite regulation of diverse processes from gene expression to enzymatic function. The formation of biomolecular condensates via phase separation (PS) acts as a general mechanism for selectively concentrating proteins, nucleic acids and metabolites in membraneless compartments and thus modulating their activity. Recent studies suggest that plants broadly exploit PS to perceive and quickly respond to their environment, altering transcriptional outputs as a function of changing environmental stimuli. Here, we provide examples of how PS properties contribute to modulating plant environmental response with a focus on gene expression at the transcriptional level and discuss the mechanisms of action of phase-separating proteins and the importance of specific protein-protein interactions for nucleation of PS.

Indexed as

Biomolecular CondensatesPlantsTranscription, GeneticGene Expression Regulation, PlantPlant ProteinsPlant Proteinsbiomolecular condensatesintrinsically disordered regionsmultivalencyphase separationprion‐like domainstranscriptional regulation

Identifiers

PMID41199588
PMCPMC12780321

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.