ArticleAntimicrobial resistance and infection control2025
Strategies and challenges in containing antimicrobial resistance in East Africa: a focus on laboratory-based surveillance.
Article in Antimicrobial resistance and infection control, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Antibiotic Resistance and the Return to a Pre-Antibiotic Era: A Critical Narrative Review of a Global Catastrophe.Biomedicines · 2026Review
- Antimicrobial Stewardship, Laboratory Surveillance, and Quality Management in Africa: A Narrative Review of Challenges and Opportunities for Integrated AMR Control.Health science reports · 2026Article
- Severe Clade I (subclade Ib) mpox in advanced HIV complicated by multidrug-resistant bacterial superinfection and ocular involvement: a case report from Uganda.Tropical medicine and health · 2026Article
- Article
- Patterns of antibiotic use for acute febrile illness in resource-limited settings: a multicenter study in DR Congo, Kenya and Uganda.Frontiers in public health · 2026Article
- Biosafety, biosecurity and antimicrobial resistance containment in Kenya: A One Health scoping review of national and subnational systems.PLOS global public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAntimicrobial resistance (AMR) is increasing worldwide, undermining strides in public health and the economy, particularly in low- and middle-income countries. Africa is the continent with the highest death rate attributed to antimicrobial-resistant infections. There is a lack of information on AMR mitigation strategies and their implementation in the region. The aim of this study was to analyze national strategies to tackle AMR with focus on AMR surveillance in the East African Community (EAC) and their implementation status including the analysis of strengths, weaknesses, opportunities, and threats.
methodsWithin our expert group (composed of representatives from the National Public Health Laboratories (NPHL), Ministries of Health of Burundi, Kenya, Rwanda, South Sudan, Tanzania, and Uganda) we used a qualitative approach to analyze AMR National Action Plans (NAPs), AMR surveillance programs, publications and reports on the AMR situation and strategies in the EAC.
resultsWe found varying levels of implementation of antimicrobial resistance (AMR) strategies among East African Community (EAC) Partner States. For example, progress in key steps for the sustainable implementation of National Action Plans on AMR (AMR-NAPs) ranged from 7% in Burundi to 94% in Kenya. The overall accomplishment of the WHO checklist for AMR surveillance also varied: 44% in South Sudan, 61% in Burundi, 89% in Rwanda, 94% in Tanzania, and 100% in both Uganda and Kenya. Within EAC Partner States, the detection of bacterial pathogens and their antimicrobial susceptibility profiles is coordinated by national reference laboratories. Most EAC countries have established AMR surveillance systems. However, challenges such as limited laboratory testing capacity, low representativeness of surveillance data, lack of integration among existing systems, and financial constraints undermine efforts to curb AMR.
conclusionsRegional collaboration among EAC Partner States is essential for an effective and sustainable response to antimicrobial resistance. Strengthening joint efforts will enable countries to share resources, harmonize surveillance systems, and address common challenges more efficiently. The EAC Regional Network of Reference Laboratories is one example of a regional mechanism that can support such collaboration. The findings of this study will inform the development of a regional AMR strategy focused on laboratory-based surveillance and help guide the prioritization of technical and financial support across the EAC region.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.