Evidence map›Paper›PMID 41199172›Full record

ArticleBMC microbiology2025

Bacillus velezensis Bac-9, isolated from kefir, possesses antifungal activity and improves resistance of tomato plant against whitefly Bemisia tabaci.

Ernesto Pérez-Rueda, Ana Roblero-Aguilar, Carlos López-González, Denisse Domínguez-García, Ángel Herrera-Gorocica, Esaú Ruiz-Sánchez, Gabriel Lizama-Uc, Silvia Tenorio-Salgado

Abstract read
In one paragraph

Article in BMC microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ernesto Pérez-RuedaInstituto de Investigaciones en Matemáticas Aplicadas y en Sistemas, Universidad Nacional Autónoma de México, Unidad Académica del Estado de Yucatán, Carretera Sierra Papacal, Mérida, Yucatán, 97302, México.
Ana Roblero-AguilarInstituto Tecnológico de Mérida, Av. Tecnológico S/N Km. 4.5, Mérida Yuc, Mérida, Yucatán, C.P. 97118, México.
Carlos López-GonzálezInstituto Tecnológico de Mérida, Av. Tecnológico S/N Km. 4.5, Mérida Yuc, Mérida, Yucatán, C.P. 97118, México.
Denisse Domínguez-GarcíaInstituto Tecnológico de Mérida, Av. Tecnológico S/N Km. 4.5, Mérida Yuc, Mérida, Yucatán, C.P. 97118, México.
Ángel Herrera-GorocicaTecnológico Nacional de México, Instituto Tecnológico de Conkal, Avenida Tecnológico s/n, Conkal, Yucatán, C.P. 97345, México.
Esaú Ruiz-SánchezTecnológico Nacional de México, Instituto Tecnológico de Conkal, Avenida Tecnológico s/n, Conkal, Yucatán, C.P. 97345, México.
Gabriel Lizama-UcInstituto Tecnológico de Mérida, Av. Tecnológico S/N Km. 4.5, Mérida Yuc, Mérida, Yucatán, C.P. 97118, México. gabriel.lu@merida.tecnm.mx.
Silvia Tenorio-SalgadoInstituto Tecnológico de Mérida, Av. Tecnológico S/N Km. 4.5, Mérida Yuc, Mérida, Yucatán, C.P. 97118, México. s.tenorio.salgado@gmail.com.

Funding

Dirección General de Asuntos del Personal Académico of the Universidad Nacional Autónoma de México IN-220523Tecnológico Nacional de México 6ef5nm(16247), M00-PR-03-R02 (21708)Tecnológico Nacional de México PR-03-R02 (21708)
6 · The paper itself

Abstract

backgroundThe Bacillus genus comprises spore-forming, Gram-positive bacteria widely recognized for their capacity to produce bioactive compounds with antimicrobial properties. This activity is primarily attributed to the synthesis of diverse molecules, including peptides, non-ribosomal peptides, and polyketides, which exhibit inhibitory effects against various pathogens. Bacillus species are ubiquitous and highly diverse, encompassing strains with significant biotechnological potential.

resultsBac-9 is a bacterial strain belonging to Bacillus genus isolated from kefir in Escárcega, Campeche, México. This strain exhibits strong antifungal activity against Fusarium equiseti, F. solani, Curvularia sp. and the oomycete, Phytophthora capsici. The genome comprises 4,059,427 bp, with a total of 4,195 coding sequences and a GC content of 46.3%. A total of 21 biosynthetic gene clusters were identified: 55% were non-ribosomal peptides (NRPs), 36% were polyketides (PKs) and 9% were NRP + PK hybrids. This bacterium produces compounds with insecticidal properties, such as thietane and acenaphthylene, which were detected by GC-MS. In tomato plants, different Bac-9 extracts activate genes involved in defense against insects and pathogens, including genes associated with the biosynthesis of jasmonic acid and salicylic acid. In addition, the extracts reduce oviposition by the whitefly Bemisia tabaci in Lycopersicon esculentum.

conclusionThis study offers valuable insights into bioactive compounds with potential for the biological control of phytopathogens and whiteflies. Overall, the bacterium emerges as a promising candidate for use in biological control strategies.

Indexed as

Antifungal AgentsBacillusHemipteraPlant DiseasesSolanum lycopersicumAnimalsDisease ResistanceFusariumGenome, BacterialPhytophthoraAntifungal AgentsBac-9Bacillus velezensisBemisia tabaci.Induced systemic resistanceKefirTomato plant

Identifiers

PMID41199172
PMCPMC12590771

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.