Trial reportBMC anesthesiology2025
The effects of ciprofol and propofol on hypoxemia during gastrointestinal endoscopy in overweight and obese patients: a randomized controlled trial.
Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ciprofol versus propofol and the risk of hemodynamic adverse events: a meta-analysis with trial sequential analysis of randomized controlled trials.BMC anesthesiology · 2026Pooled it
- An Oxycodone-Based Conscious Analgesia Strategy with Supplemental Low-Dose Propofol Improves Safety in Elderly Obese Patients Undergoing Gastroscopy: A Prospective Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Effects of ciprofol versus propofol sedation on hypoxaemia and hypotension in elderly patients undergoing bidirectional endoscopy: protocol for a randomized controlled trial.Frontiers in medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundOverweight and obesity are prevalent modern health issues. It has been suggested that individuals who are overweight or obese are more likely to experience hypoxemia during gastrointestinal endoscopy. Ciprofol has demonstrated advantages over propofol in endoscopic procedures, including lower rates of respiratory depression among normal-weight populations. This study aimed to compare the incidence of hypoxemia between ciprofol and propofol in overweight and obese patients undergoing gastrointestinal endoscopy.
methodsA total of 176 patients were randomly assigned to receive either ciprofol or propofol. The primary outcome was the incidence of hypoxemia, defined as pulse oxygen saturation (SpO
resultsAlthough the incidence of hypoxemia (SpO
conclusionsThe findings of this study indicate that ciprofol offers sedation effects comparable to those of propofol, without significantly altering the incidence of hypoxemia in overweight and obese patients undergoing gastrointestinal endoscopy. However, additional evidence is required to validate these findings due to the limitations posed by the sample size.
trial registrationThe study was registered with the Chinese Clinical Trial Registry at www.chictr.org.cn (registration date: July 22nd 2024, registration number: ChiCTR2400087170).
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