ArticleCJEM2026
Missing the needle in the haystack: diagnostic errors in neurological emergencies within Canadian emergency departments.
Article in CJEM, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
objectivesTimely diagnosis of neurological emergencies in the emergency department (ED) remains a critical skill for physicians. Errors in diagnosing neurological conditions can lead to severe patient harm, including permanent disability or death. Conversely, over-investigation may contribute to unnecessary imaging, increased healthcare costs, and reduced departmental efficiency. Understanding the nature and frequency of these diagnostic errors is essential to improving clinical practice and patient safety. The primary objective of this study was to describe the nature of diagnostic errors for neurologic emergencies in the ED.
methodsThis study conducted a five-year descriptive analysis of closed medicolegal cases from the Canadian Medical Protective Association (CMPA) database involving missed or delayed neurological diagnoses in Canadian EDs between January 2019 and December 2023. Cases were reviewed for patient demographics, primary neurological condition, provider type, patient-reported concerns, and expert reviewer commentary. Allegations and identified deficiencies were coded thematically and analyzed for common patterns and clinical pitfalls.
resultsA total of 143 cases met inclusion criteria. The most frequently missed diagnoses were cerebral infarcts (34%), traumatic intracranial injuries (22%), and central nervous system infections (15%). Cauda equina syndrome accounted for 8% of cases. Patient concerns frequently mirrored expert peer review findings, which identified deficient assessment, failure to consider key differential diagnoses, and inadequate diagnostic testing as the top contributing factors. Many cases involved atypical or non-specific presentations that may have led providers to prematurely rule out serious pathology.
conclusionDiagnostic errors in neurological emergencies remain an important contributor to patient harm and medico-legal risk in Canadian EDs. A better understanding of the factors that contribute to these diagnostic errors can support physicians in improving their clinical reasoning and documentation. These insights may ultimately empower Canadian emergency physicians to refine their diagnostic approach and enhance patient outcomes in both emergency and non-emergency settings.
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Registered trials
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