Evidence map›Paper›PMID 41198989›Full record

Observational studyDigestive diseases and sciences2026

Prospective, Observational Study of the Efficacy, and Tolerability of a Same-Day, Low-Volume D-Sorbitol, Ascorbic Acid, and Sodium Picosulfate Regimen for Colonoscopy Bowel Preparation.

Jae Hyun Kim, Sang Wook Ahn, Seong Dae Lee, Sung Woo Choi, Seun Ja Park

Abstract readObservational StudyMulticenter Study
In one paragraph

Observational study in Digestive diseases and sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jae Hyun KimDepartment of Internal Medicine, Kosin University College of Medicine, Busan, South Korea.
Sang Wook AhnHangsarang Colorectal Clinic, Goyang, South Korea.
Seong Dae LeeSeoulhang Clinic, Goyang, South Korea.
Sung Woo ChoiGibbeum Hospital, Seoul, South Korea.
Seun Ja ParkDepartment of Internal Medicine, Kosin University College of Medicine, Busan, South Korea. parksj6406@daum.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsLow-volume, single-dose bowel preparations may improve patient convenience and compliance while maintaining cleansing quality. This study evaluated the efficacy and safety of a same-day, low-volume, single-dose D-sorbitol, ascorbic acid, and sodium picosulfate bowel cleansing regimen in routine outpatient practice.

methodsFrom May 2022 to July 2025, a prospective, multicenter post-marketing surveillance was conducted in four centers in Korea. Adult outpatients aged 19 to 80 years scheduled for elective colonoscopy and prescribed the study regimen were enrolled, excluding those with suspected bowel obstruction or severe comorbidities. The regimen consisted of 230 mL of reconstituted solution followed by 460 mL of water, administered 4-5 h before colonoscopy. Cleansing quality was graded using the Harefield Cleansing Scale (HCS); adequate cleansing was defined as Grade A or B. Secondary outcomes were regimen completion and adverse events. All variables were summarized using descriptive statistics.

resultsA total of 608 patients (mean age 53.0 ± 12.9 years; 49.8% male; mean BMI 23.8 ± 3.2 kg/m

conclusionThis prospective, observational study demonstrated that a same-day, low-volume D-sorbitol, ascorbic acid, and sodium picosulfate bowel cleansing regimen showed high efficacy, excellent completion rates, and a favorable safety profile in outpatient colonoscopy practice. This could represent a convenient alternative to traditional split-dose preparations, potentially improving patient compliance.

Indexed as

Ascorbic AcidCatharticsCitratesColonoscopyOrganometallic CompoundsPicolinesSorbitolAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesRepublic of KoreaAscorbic AcidCatharticsCitratesOrganometallic CompoundsPicolinespicosulfate sodiumSorbitolAscorbic acidCatharticsColonoscopyD-SorbitolSame-day bowel preparationSodium picosulfate

Identifiers

PMID41198989
PMCPMC13144189

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.