Evidence map›Paper›PMID 41198965›Full record

ReviewAnalytical and bioanalytical chemistry2026

Photon density wave spectroscopy as process analytical technology: a review of recent advances in technology and application.

Thomas Schiewe, Aaron Justin Koenig, Björn Weiske, Roland Hass

Abstract readReview
In one paragraph

Review in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Thomas SchieweChair of Bioprocess Engineering, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany. schiewe@campus.tu-berlin.de.ORCID http://orcid.org/0000-0002-3908-7591
Aaron Justin KoeniginnoFSPEC Transfer Lab, Institute of Chemistry, University of Potsdam, Potsdam, Germany.ORCID http://orcid.org/0000-0003-3781-5759
Björn WeiskeCorden BioChem International GmbH, Brüningstr. 50, 65929, Frankfurt, Germany.ORCID http://orcid.org/0000-0003-0166-8734
Roland HassPDW Analytics GmbH, Geiselbergstraße. 4, 14476, Potsdam, Germany. rh@pdw-analytics.de.ORCID http://orcid.org/0000-0002-0226-6641

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Photon density wave (PDW) spectroscopy is a calibration-free method for the simultaneous, absolute, and independent quantification of the optical absorption coefficient and the reduced scattering coefficient of highly light scattering materials. It allows for dilution-free particle sizing in concentrated liquid systems. Thus, it is beneficial as an inline process analytical technology (PAT). A brief comparison to other particle sizing technologies, the theoretical background of PDW spectroscopy, the current technical status, and limitations and technical challenges are reviewed. In addition, a comparative overview of the recent applications of PDW spectroscopy as PAT for chemical, biotechnological, and food processing is provided.

Indexed as

EmulsionsFermentationInlineParticle sizingPATPDW spectroscopySuspensions

Identifiers

PMID41198965
PMCPMC12774946

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.