ArticleNPJ precision oncology2025
Enhancing translational research in metastatic cancer through an open science environment: the UPTIDER experience.
Article in NPJ precision oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04531696 (UZ/KU Leuven Program for Post-mortem Tissue Donation to Enhance Research), which is not on this map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
UZ/KU Leuven Program for Post-mortem Tissue Donation to Enhance Research
Who cites it
1 citing paper in PubMed.
- Enhancing translational research in metastatic cancer through an open science environment: the UPTIDER experience.NPJ precision oncology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Funding
Abstract
Translational research in metastatic cancer is limited by insufficient metastatic samples. Post-mortem tissue donation programs address this issue by facilitating comprehensive sample collection. Sustaining such programs requires an open science environment (OSE) to ensure multidisciplinary collaboration, research standards, and patient privacy. While often seen at publication, we demonstrate the benefit of developing upstream phases by presenting the OSE from our institutional post-mortem tissue donation program UPTIDER (NCT04531696). It contains (i) an electronic case report form to capture >750 clinical features including treatment lines and metastases, (ii) a lab information management system to track >100 metadata features from logistical to anatomical information, (iii) a code versioning system, (iv) long-term data and sample storage, and (v) code and data sharing upon publication. By ensuring latest access to information, our OSE reflects the potential to accelerate translational research. While our OSE was tailored for UPTIDER, we believe our experiences can inspire others.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.