Evidence map›Paper›PMID 41198879›Full record

ArticleNature2026

An ATP-gated molecular switch orchestrates human mRNA export.

Ulrich Hohmann, Max Graf, László Tirián, Belén Pacheco-Fiallos, Ulla Schellhaas, Laura Fin, Dominik Handler, Alexander W Phillips, Daria Riabov-Bassat, Rupert Faraway and 5 more

Abstract read
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Article
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  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. The SPARK complex forms the molecular basis of vertebrate fertilization.bioRxiv : the preprint server for biology · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Viral interference of nucleocytoplasmic transport.The Journal of biological chemistry · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Ulrich HohmannResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. u.hohmann@imb-mainz.de.ORCID 0000-0003-2124-1439
Max GrafResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0009-0001-0756-5173
László TiriánInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.
Belén Pacheco-FiallosResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0001-5398-5809
Ulla SchellhaasResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-9684-9839
Laura FinResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Dominik HandlerInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-1059-4960
Alexander W PhillipsResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-6689-9632
Daria Riabov-BassatResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.
Rupert FarawayResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-1217-795X
Thomas PühringerResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0001-9127-9120
Michael-Florian SzalayResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-6310-0610
Elisabeth RoitingerResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.ORCID 0000-0002-3405-7801
Julius BrenneckeInstitute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria. julius.brennecke@imba.oeaw.ac.at.ORCID 0000-0002-5141-0814
Clemens PlaschkaResearch Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria. clemens.plaschka@imp.ac.at.ORCID 0000-0002-6020-9514

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nuclear export of mRNA is an important step in eukaryotic gene expression

Indexed as

Adenosine TriphosphateRNA, MessengerRNA TransportActive Transport, Cell NucleusCell NucleusDEAD-box RNA HelicasesHeLa CellsHumansModels, MolecularNuclear PoreNuclear ProteinsRibonucleoproteinsAdenosine TriphosphateDDX39B protein, humanDEAD-box RNA Helicasesmessenger ribonucleoproteinNuclear ProteinsRibonucleoproteinsRNA, Messenger

Identifiers

PMID41198879
PMCPMC12823420

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.