Inhibiting invasive fish reproduction via germ cell xenotransplantation and hybrid lethality.

Yuichi Amano, Haruto Baba, Daisuke Kishi, Yushi Shimomura, Goro Yoshizaki

Abstract read

In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Germ cell manipulation in farmed fishes.The Journal of reproduction and development · 2026
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yuichi AmanoDepartment of Marine Biosciences, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato, Tokyo, 108-8477, Japan.

Haruto BabaDepartment of Marine Biosciences, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato, Tokyo, 108-8477, Japan.

Daisuke KishiGifu Prefectural Research Institute for Fisheries and Aquatic Environments, Gifu, 501-6021, Japan.

Yushi ShimomuraGifu Prefectural Research Institute for Fisheries and Aquatic Environments, Gifu, 501-6021, Japan.

Goro YoshizakiDepartment of Marine Biosciences, Tokyo University of Marine Science and Technology, 4-5-7 Konan, Minato, Tokyo, 108-8477, Japan. goro@kaiyodai.ac.jp.

Funding

Grant-in-Aid for JSPS Fellows JP22J12808Grant-in-Aid for Scientific Research (KAKENHI) JP23H00344

6 · The paper itself

Abstract

Invasive alien fish constitute a major problem in the conservation of aquatic ecosystems. The most common method of exterminating invasive fish is physical capture by fishing gear; however, it is extremely difficult to eradicate them. Here, we developed a novel methodology to inhibit the reproduction of invasive fish by releasing surrogate males of the same species, which produce sperm of different species, into rivers, allowing them to produce lethal hybrids through natural spawning. This study focused on rainbow trout, an invasive fish that negatively impacts ecosystems worldwide. Since rainbow trout × brown trout hybrids are lethal, surrogate rainbow trout producing brown trout sperm were created by germline stem cell transplantation. Releasing the surrogate males into an experimental river inhabited by wild-type rainbow trout females revealed that they naturally mated and produced lethal hybrid offspring. This is a novel and powerful methodology for eradicating invasive fish.

Indexed as

Germ CellsIntroduced SpeciesOncorhynchus mykissReproductionTransplantation, HeterologousAnimalsFemaleMaleSpermatozoa

Identifiers

PMID41198865

DOI10.1038/s41598-025-22789-3

PMCPMC12592397

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-ND

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.