ArticleScientific reports2025
Remodeling of calcium signaling and store operated calcium entry as a consequence of human neural progenitor cell differentiation.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Chronic Fluoride Exposure Disrupts Calcium-Dependent Neurodevelopmental Signalling and Brain Proteomic Architecture: Multi-Target Modulation by Naringin.Biological trace element research · 2026Article
- Integration of Metabolic Pathways and Micronutrient Signals Influences Neurodevelopment by Modulating Neural Stem Cell Dynamics.Molecular neurobiology · 2026Review
- DNA Methylation Landscape of ReNcell Common Neural Progenitor Cell Lines Reveals Distinct Lineage Bias.Biology · 2026Article
- Age-dependent functional and transcriptional differences in intestinal mesenchymal stromal cells during early postnatal development in piglets.Frontiers in cell and developmental biology · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The differentiation of neural progenitor cells into glial and neuronal lineages is a fundamental process in neurodevelopment. This complex process is tightly regulated by several signaling pathways, including calcium signaling. Calcium signaling not only regulates neural progenitor proliferation and survival but also regulates gene expression changes that drive the differentiation process and cell fate. One calcium signaling pathway that has been associated with neural progenitor cells proliferation and differentiation is store-operated calcium entry (SOCE), mediated by STIM and ORAI proteins. Using human neural progenitor ReNcell VM model expressing a genetically encoded calcium indicator and high content imaging methods, calcium signaling changes associated with neuronal differentiation were assessed. Differentiated cells exhibited increased spontaneous Ca
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Registered trials
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