ArticleScientific reports2025
The global burden of hearing loss and its comorbidity with chronic diseases: a comprehensive analysis from 1990 to 2021.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Presbycusis Across the Lifespan: Genetic, Molecular, and Multi-Omics Contributions.Audiology research · 2026Review
- Determinants of poor speech discrimination in a primary care otolaryngology population: a retrospective observational study.BMC primary care · 2026Observational
- Cochlear synaptic vulnerability scales with pathological noise intensity in a noise-induced hearing loss model.Genes & genomics · 2026Article
- Audiology at the Intersection of Labor, Revenue, and Professional Taxonomy.Seminars in hearing · 2026Review
- Development and empirical validation of a multi-criteria decision-making model for the assessment of noise-induced hearing loss (NIHL) in high-exposure industrial settings.BMC public health · 2026Article
- Associations of combined hearing loss and depression with cognitive impairment among older adults: a sex difference analysis based on evidence from CHARLS.BMC public health · 2026Article
- Chitosan Protects Peripheral Nerves Against Damage Induced by Diabetes Mellitus.Life (Basel, Switzerland) · 2025Article
- Advances in Research on the Association between Age-Related Hearing Loss and Risk of Falls and Fractures.Noise & healthReview
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Authors and funding
6 authors.
Funding
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Abstract
Age-related hearing loss (HL) is an increasing contributor to the global burden of disease in aging populations. Its interactions with major chronic diseases remain insufficiently characterized. We analyzed data from the Global Burden of Disease 2021 study for adults aged ≥ 45 years. YLDs for HL, diabetes, cardiovascular diseases (CVD), stroke, and depressive disorders were examined from 1990 to 2021. Data were stratified by age, sex, and region. Multivariate regression models and Pearson correlations were applied to evaluate associations, and a linear forecast projected HL burden to 2030. Visualizations included temporal trends, boxplots, and correlation heatmaps. Between 1990 and 2021, HL YLDs increased from 28.7 million to 67.9 million (+ 136.7%). Diabetes (+ 311.9%), CVD (+ 123.8%), and stroke (+ 112.6%) also rose substantially. Regression analysis indicated significant associations between HL and stroke (β = 1.798, p = 0.0010) and depression (β = 0.218, p < 0.001), whereas diabetes showed no independent effect and CVD displayed a negative relationship (β = -1.374, p = 0.0016). Correlation analyses revealed regional clustering, with HL aligning more closely with stroke than with diabetes or CVD. Forecasting projected HL YLDs to reach 75.6 million by 2030, underscoring its growing impact. HL has become a major global health challenge in aging populations, strongly linked to multimorbidity, particularly stroke and depression. Integrating auditory health into chronic disease frameworks and healthy aging strategies is essential to reduce future disease burden.
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