ArticleNature communications2025
Molecular basis for selection and inhibition of HIV-1 escape virus by T cells and KIR2DL2
Abstract read
In one paragraph
Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Multistep coevolution of HIV-1 and human leukocyte antigen-C-restricted HIV-1-specific CD8PNAS nexus · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors.
Takayuki Chikata *Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.ORCID http://orcid.org/0000-0001-8907-1320
Kimiko Kuroki *Laboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Nozomi Kuse *Division of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.ORCID http://orcid.org/0000-0003-3852-2288
Anna E KliszczakNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Wayne PaesNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Nanami TomiokaLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Robert ParkerNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Aure AflaloNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0002-7158-6868
Tomohiro AkahoshiDivision of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.
Yu ZhangDivision of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.ORCID http://orcid.org/0000-0002-5446-5650
Ryoya YamashitaLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Ryuma SakataLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Hiroki KusakaLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Yosuke WatanabeLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Annalisa NicastriNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Haruki MatsubaraLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Toyoyuki OseLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.ORCID http://orcid.org/0000-0002-2001-9388
Shunsuke KitaLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.ORCID http://orcid.org/0000-0003-3969-302X
Shinichi OkaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Hiroyuki GatanagaAIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Zhansong LinDivision of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan.
Nicola TernetteNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
Persephone BorrowNuffield Department of Clinical Medicine, University of Oxford, Oxford, UK. persephone.borrow@ndm.ox.ac.uk.ORCID http://orcid.org/0000-0002-3877-9780
Katsumi MaenakaLaboratory of Biomolecular Science, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. maenaka@pharm.hokudai.ac.jp.ORCID http://orcid.org/0000-0002-5459-521X
Masafumi TakiguchiDivision of International Collaboration Research and Tokyo Joint Laboratory, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto/Tokyo, Japan. masafumi@kumamoto-u.ac.jp.ORCID http://orcid.org/0000-0002-8516-6442
Funding
Targeting 5' leader-encoded defective ribosomal products for HIV T cell vaccinesR01AI118549 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI SHAW, GEORGE M · 2016 to 2020
$3.6MNatural killer cell regulation of the germinal center HIV neutralizing antibody responseR01AI147778 · NIAID · CHILDREN'S MERCY HOSP (KANSAS CITY, MO) · PI BRADLEY, TODD CHRISTOPHER · 2020 to 2024
$3.6MJapan Agency for Medical Research and Development (AMED) JP17am0101093Japan Agency for Medical Research and Development (AMED) JP20ae0101047Japan Agency for Medical Research and Development (AMED) JP21fk0410044Japan Agency for Medical Research and Development (AMED) JP22ama121037Japan Agency for Medical Research and Development (AMED) JP22fk0410053Japan Agency for Medical Research and Development (AMED) JP23wm0225039Japan Agency for Medical Research and Development (AMED) JP24fk0410069MEXT | Japan Society for the Promotion of Science (JSPS) 20H03726NIAID NIH HHS R01 AI118549NIAID NIH HHS R01 AI147778
Abstract
NK cells and CD8
Indexed as
CD8-Positive T-LymphocytesHIV-1HIV InfectionsImmune EvasionKiller Cells, NaturalReceptors, KIR2DL2HLA-C AntigensHumansMutationReceptors, Antigen, T-CellVirus ReplicationHLA-C AntigensKIR2DL2 protein, humanReceptors, Antigen, T-CellReceptors, KIR2DL2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.