SynthesisThe Journal of international medical research2025
A low perioperative fraction of inspired oxygen reduces the incidence of postoperative atelectasis in patients undergoing abdominal surgery under general anesthesia: A systematic review and meta-analysis.
Synthesis in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Association Between Intraoperative Arterial Oxygen Tension and Postoperative Opioid Consumption: A Large-Scale Cohort Study Using Overlap Weighting Analysis.Medicina (Kaunas, Lithuania) · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveTo determine the relative risk of atelectasis after abdominal surgery associated with perioperative fraction of inspired oxygen.MethodsOur meta-analysis was registered with the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD 42021270703). The PubMed, Cochrane Library, EMBASE, and Web of Science databases were searched for randomized controlled trials reporting the influence of perioperative fraction of inspired oxygen on the incidence of postoperative atelectasis in patients who had undergone abdominal surgery under general anesthesia. We used a random-effect model to calculate the relative risk of postoperative atelectasis. Subgroup analyses were performed according to age, ventilation strategy, surgical incision site, and surgery duration.ResultsFinally, we included 10 randomized controlled trials involving 3471 participants. Compared with the high fraction of inspired oxygen group (60%-100%), a reduced atelectasis incidence after abdominal surgery was observed in the low fraction of inspired oxygen group (20%-40%). Patients with an average age ≥60 years benefited more from a low fraction of inspired oxygen in terms of prevention of postoperative atelectasis compared with those with an average age <60 years (risk ratio: 1.47; 95% confidence interval: 1.14-1.90). Patients undergoing lower abdominal surgery benefited from a low perioperative fraction of inspired oxygen (risk ratio: 1.43; 95% confidence interval: 1.14-1.80).ConclusionsA low perioperative fraction of inspired oxygen may decrease the risk of atelectasis after lower abdominal surgery performed under general anesthesia, especially in patients with an average age <60 years.
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