Evidence map›Paper›PMID 41198583›Full record

ArticleVeterinary and comparative oncology2026

Phase 1 Dose Escalation of Single-Agent Mechlorethamine in Dogs With Lymphoma.

Laura E Chadsey, Paul R Hess, Joanne L Intile

Abstract readClinical Trial, Veterinary
In one paragraph

Article in Veterinary and comparative oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Laura E ChadseyDepartment of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
Paul R HessDepartment of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.
Joanne L IntileDepartment of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, North Carolina, USA.ORCID https://orcid.org/0000-0002-6291-8592

Funding

Veterinary Cancer Society
6 · The paper itself

Abstract

Mechlorethamine is commonly prescribed to dogs at 3 mg/m

Indexed as

Antineoplastic AgentsAntineoplastic Agents, AlkylatingDog DiseasesLymphomaMechlorethamineAnimalsDogsDose-Response Relationship, DrugFemaleMaleMaximum Tolerated DoseAntineoplastic AgentsAntineoplastic Agents, AlkylatingMechlorethaminecancer treatmentcaninechemotherapyhaematopoietic neoplasia

Identifiers

PMID41198583
PMCPMC12875749

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.