Evidence map›Paper›PMID 41198410›Full record

ArticleThe European respiratory journal2025

From fibroblast foci to dense scars: PAK2-activated fibroblasts drive fibrosis progression in idiopathic pulmonary fibrosis.

Xuexi Zhang, Xue Liu, Paul W Noble

Abstract readLetterComment
In one paragraph

Article in The European respiratory journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Xuexi ZhangDepartment of Medicine and Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Xue LiuDepartment of Medicine and Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Paul W NobleDepartment of Medicine and Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA Paul.Noble@cshs.org.

Funding

Molecular Regulation of Progressive Pulmonary FibrosisR35HL150829 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Paul Wesley Noble · 2020 to 2026
$5.7M
ZIP8-dependent Zinc Metabolic Regulation in Alveolar Progenitor Cell Aging and FibrosisR01AG078655 · NIA · CEDARS-SINAI MEDICAL CENTER · PI Carol Jiurong Liang, Paul Wesley Noble · 2022 to 2026
$2.7M
NHLBI NIH HHS R35 HL150829NIA NIH HHS R01 AG078655
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID41198410
PMCPMC12591135

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.