Evidence map›Paper›PMID 41197836›Full record

ArticleUrology2026

Clinician- and Geographic-level Variation in Utilization of Sacral Neuromodulation and OnabotulinumtoxinA Injections Among Medicare Beneficiaries With Overactive Bladder.

Leo D Dreyfuss, Lufan Wang, Farnoosh Nik-Ahd, Abigail Shatkin-Margolis, Kenneth Covinsky, W John Boscardin, Anne M Suskind

Abstract read
In one paragraph

Article in Urology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Leo D DreyfussDepartment of Urology, Weill Cornell Medical Center, New York, NY. Electronic address: LDD9009@nyp.org.
Lufan WangDepartment of Urology, University of California, San Francisco, CA.
Farnoosh Nik-AhdDepartment of Urology, University of California, San Francisco, CA.
Abigail Shatkin-MargolisDepartment of Obstetrics and Gynecology, University of California, San Francisco, CA.
Kenneth CovinskyDivision of Geriatrics, University of California, San Francisco, CA.
W John BoscardinDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA.
Anne M SuskindDepartment of Urology, University of California, San Francisco, CA.

Funding

UCSF-Kaiser Urological Epidemiology Research Career Development ProgramK12DK111028 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, ALISON · 2016 to 2025
$5.3M
Determinants of outcomes for older and frail older adults with refractory overactive bladderR56AG076501 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SUSKIND, ANNE M. · 2023 to 2023
$474k
NIA NIH HHS R56 AG076501NIDDK NIH HHS K12 DK111028
6 · The paper itself

Abstract

objectiveTo evaluate clinician- and geographic-level variation in utilization of sacral neuromodulation (SNM) and onabotulinumtoxinA injections as index treatment for overactive bladder (OAB) among United States Medicare beneficiaries.

methodsThis is a cross-sectional study of a 100% sample of fee-for-service Medicare beneficiaries undergoing first-time SNM test procedures or onabotulinumtoxinA injections from 2014-2016. The primary outcomes were clinician- and geographic-level variation in utilization of SNM or onabotulinumtoxinA injections. Secondary outcomes included variation in use of SNM test procedures (percutaneous nerve evaluation [PNE] and stage 1 permanent tined lead placement [stage 1]). Geographic region was defined using hospital referral regions (HRRs). Mixed-effect logistic regression models were used to calculate the median odds ratio (MOR) for clinician and HRR (higher MOR = greater variability between groups) and to identify individual-level predictors of utilization.

resultsOverall, 48,580 Medicare beneficiaries underwent SNM (47.1%) or onabotulinumtoxinA injections (52.9%) during the study period. There was a considerable amount of variation according to clinician and HRR, which were more influential than patient-level characteristics in the type of procedure received. The adjusted MOR for SNM versus onabotulinumtoxinA injections was 33.1 for clinician and 4.24 for HRR. For stage 1 versus PNE, the MOR was 13.12 for clinician and 2.44 for HRR.

conclusionAmong Medicare beneficiaries undergoing first-time SNM or onabotulinumtoxinA injections, there was considerable variation according to performing clinician and geographic region. These findings suggest that non-clinical variables-who a patient sees and where they live-are significant drivers of minimally invasive OAB therapy utilization in the United States.

Indexed as

Botulinum Toxins, Type AElectric Stimulation TherapyNeuromuscular AgentsPractice Patterns, Physicians'Urinary Bladder, OveractiveAgedAged, 80 and overCross-Sectional StudiesFemaleHumansLumbosacral PlexusMaleMedicareUnited StatesBotulinum Toxins, Type ANeuromuscular Agentsonabotulinum toxin A

Identifiers

PMID41197836
PMCPMC12820582

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.