Evidence map›Paper›PMID 41197660›Full record

ReviewGlobal spine journal2026

Tranexamic Acid Versus no Tranexamic Acid in Spinal Tumor and Metastasis Surgery-Meta-Analysis.

Anna Łajczak, Paweł Łajczak, Oguz Kagan Sahin, Ayesha Ayesha, Newton Godoy Pimenta, Ramon Guerra Barbosa

Abstract readReview
In one paragraph

Review in Global spine journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna ŁajczakMedical University of Silesia, Katowice, Poland.
Paweł ŁajczakMedical University of Silesia, Katowice, Poland.
Oguz Kagan SahinEdremit State Hospital, Balikesir, Turkey.
Ayesha AyeshaShifa College of Medicine, Islamabad, Pakistan.
Newton Godoy PimentaNeurosurgery Division, University of Sherbrooke, Sherbrooke, QC, Canada.
Ramon Guerra BarbosaNeurosurgery Division, Hôpital de Chicoutimi, Saguenay, QC, Canada.ORCID 0000-0001-8356-5653

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Study DesignMeta-analysis.ObjectivesSpinal tumors and metastases remain a challenge for spine surgeons, with a significant risk of perioperative blood loss, which might require blood transfusions and lead to increased complications. Tranexamic acid (TXA) is an antifibrinolytic agent widely used in various surgical procedures; however, its efficacy in spinal oncology surgery remains unclear. This meta-analysis aims to evaluate the clinical effectiveness of TXA on perioperative outcomes, mainly blood loss, among patients with oncological spines undergoing surgery.MethodsPubMed, Scopus, and Web of Science were systematically searched from inception for eligible articles. We included studies assessing TXA vs no TXA or placebo on perioperative outcomes among patients with spinal tumors or metastases.ResultsAfter a comprehensive search, seven studies were included. Blood loss (MD -111.75 mL; 95% CI -217.08 to -6.43;

Indexed as

blood lossmeta-analysismetastasisspinal tumor surgerytranexamic acid

Identifiers

PMID41197660
PMCPMC12592104

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.