Evidence map›Paper›PMID 41197127›Full record

ArticleACS applied materials & interfaces2025

Imaging Sensing of Cadmium-Induced Single Cancer Stem Cells in Tumor Spheroid Fabricated by 3D Bioprinting.

Minji Kwon, Joon Myong Song

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Minji KwonCollege of Pharmacy, Seoul National University, Seoul 08826, South Korea.ORCID 0009-0009-3572-7705
Joon Myong SongCollege of Pharmacy, Seoul National University, Seoul 08826, South Korea.ORCID 0000-0002-9896-5892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigates the formation of cadmium-induced CSCs within individual HepG2 tumor spheroids, which are fabricated using 3D bioprinting of HepG2 cancer cell-laden hydrogel composed of alginate and gelatin. The quantification of cadmium-induced single CSCs in single spheroids was performed through multicolor single-cell 3D imaging of CSC biomarkers, without the need to isolate spheroids from the hydrogel. Single HepG2 CSCs exhibiting the aldehyde dehydrogenase 1 (ALDH1)

Indexed as

BioprintingCadmiumNeoplastic Stem CellsPrinting, Three-DimensionalSpheroids, CellularHep G2 CellsHumansHydrogelsCadmiumHydrogels3D bioprintingcadmiumcancer stem cellsin situ detectiontumor spheroid imaging

Identifiers

PMID41197127
PMCPMC12635960

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.