Evidence map›Paper›PMID 41197116›Full record

ReviewPerfusion2026

The internal mammary artery - use as a free graft in coronary artery bypass grafting - evidence, technical considerations and controversies.

Manoraj Navaratnarajah, Fadi Ibrahim Al-Zubaidi, Shahzad G Raja

Abstract readReview
In one paragraph

Review in Perfusion, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Manoraj NavaratnarajahDepartment of Cardiac Surgery, St Thomas Hospital, London, UK.
Fadi Ibrahim Al-ZubaidiDepartment of Cardiac Surgery, John Radcliffe Hospital, Oxford, UK.ORCID 0000-0002-3455-4648
Shahzad G RajaDepartment of Cardiac Surgery, Harefield Hospital, Middlesex, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundIn-situ internal mammary artery (IMA) grafting remains the gold standard in coronary artery bypass grafting (CABG), particularly for left anterior descending artery revascularisation. However, the role of free-IMA grafts-especially free right IMA (RIMA) and select cases of free left IMA (LIMA)-has expanded in response to anatomical and technical constraints. This narrative review synthesises current evidence on free-IMA use during CABG.MethodsA structured literature search was conducted using PubMed (1946-2025) and Embase (1974-2025), supplemented by Web of Science, Google Scholar, and thesis repositories. Studies were included if they reported outcomes related to free-IMA grafting, regardless of pump status or harvesting technique. Of 74 eligible studies, 9 chosen studies specifically reported free-RIMA outcomes and were analysed in detail.ResultsFree-RIMA grafting demonstrated excellent long-term patency (up to 96%) and favourable survival outcomes when used as composite or direct aorto-coronary grafts. Multi-arterial grafting (MAG) and total arterial grafting (TAG) strategies incorporating free-IMA conduits were associated with reduced major adverse cardiac events (MACE) and improved freedom from repeat revascularisation. Despite these benefits, uptake of free-IMA techniques remains low in Europe and North America, often limited by institutional preferences and operator experience.ConclusionCurrent evidence supports the selective use of free-IMA grafts in CABG, particularly when in-situ deployment is not feasible. Prospective studies are needed to validate long-term outcomes beyond 10 years, compare free-IMA with radial artery grafts, and define optimal arterial configurations for durable revascularisation.

Indexed as

Coronary Artery BypassMammary ArteriesHumansarterial graftingcardiac surgical procedurescoronary artery bypass graftingmammary arteriestreatment outcome

Identifiers

PMID41197116
PMCPMC13323918

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.