ArticleACS nano2025
Assessment of Acute Stress and Chronic Stress for Mental Health Management by a Fully Integrated Wearable Biosystem.
Article in ACS nano, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Recent Advances in Biomimetic Hydrogels for Bioelectronics and Human-Machine Interactions.Gels (Basel, Switzerland) · 2026Review
- From Reactive to Proactive Healthcare: Synergizing Wearable Biomarkers and Machine Learning in Digital Therapeutics.Bioengineering (Basel, Switzerland) · 2026Review
- Wearable Electronics for Precision Diagnosis Through Advanced Manufacturing and Integration.Nano-micro letters · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
24 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mental stress has been a paramount concern worldwide, serving as a critical element for the optimal functioning and thriving of families, communities, and societies. However, the evaluation of the mental stress state in current clinical practice relies on symptom criteria associated with self-reported psychometric tools and behavioral manifestations, which raises the concerns of both accuracy issue and difficulty in identifying classifications. Continuous and quantitative assessments of mental stress-related physical/biomarkers based on wearable technologies is a very feasible way to solve the hurdle, while the implementation of such technology at clinical scales remains quite challenging and has yet to be documented. Herein, we report the collection of advances in sensing strategies, system integration, and model construction for mental health monitoring and management. A set of physical/biomarkers (cortisol, glucose, body temperature, and heart rate) are selected based on the systematic studies on the stress-correlated physiological pathways to form the marker panel. Corresponding stable and sustainable sensing systems are established upon the optimization of nanomaterials and nanostructure design. Comprehensive indicators are further generated based on algorithm bonuses for acute and chronic stress assessment. The fully integrated reusable wearable biosystem demonstrates its effectiveness in identifying, quantifying, and tracking the prognosis of stress in paradigmatic stress scenarios and clinical applications of social anxiety disorder/depression. The technology reported here presents a promising solution for customized mental stress management to facilitate the development of healthcare in psychological well-being.
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Registered trials
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