Trial reportEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025
Impact of early FAST ultrasound on severe trauma outcomes: a randomized trial in a low-resource African emergency setting (The ALIFAST Trial).
Trial report in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- From ALIFAST to GA²LIFAST: expanding the system impact of point-of-care ultrasound in trauma care.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
purposeTrauma is a leading cause of mortality worldwide, especially in low- and middle-income countries (LMICs), where diagnostic resources are limited. This study evaluated whether early Focused Assessment with Sonography for Trauma (FAST) reduces mortality and resource use in polytrauma patients in a low-resource setting.
methodsWe conducted a single-center, randomized controlled trial among adults with severe trauma admitted to the emergency department of a tertiary hospital in Morocco. Patients were randomized to standard care or a protocol incorporating FAST during initial triage. The primary outcome was in-hospital mortality. Secondary endpoints included 30-day mortality, time to surgery, CT use, transfusion needs, and hospital stay. Multivariable logistic regression and survival analyses were performed.
resultsA total of 157 patients were enrolled (77 control, 80 FAST). In-hospital mortality was significantly lower in the FAST group (39.2% vs. 66.2%, p = 0.001). Thirty-day mortality was also reduced (45.6% vs. 72.7%, p = 0.001). FAST use was associated with decreased odds of in-hospital death (adjusted OR 0.48; p = 0.050) and improved survival time (HR 0.56; p = 0.014). Fewer patients underwent CT in the FAST group (82.5% vs. 96.1%, p = 0.006), and time to surgery was shorter (5.16 vs. 9.82 h, p < 0.001).
conclusionEarly use of FAST significantly reduced mortality, CT use, and surgical delays. These findings support guideline recommendations for integrating FAST into trauma triage protocols, particularly in LMICs.
trial registrationPACTR202507728817990 (retrospectively registered).
Indexed as
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Registered trials
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