Evidence map›Paper›PMID 41196350›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

The role of active mRNA-ribosome dynamics and closing constriction in daughter chromosome separation in

Chathuddasie I Amarasinghe, Mu-Hung Chang, Jaana Männik, Scott T Retterer, Maxim O Lavrentovich, Jaan Männik

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The role of active mRNA-ribosome dynamics and closing constriction in daughter chromosome separation inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chathuddasie I AmarasingheDepartment of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996.ORCID 0000-0002-8746-1621
Mu-Hung ChangDepartment of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996.ORCID 0000-0003-3818-1313
Jaana MännikDepartment of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996.
Scott T RettererCenter for Nanophase Materials Sciences, Oak Ridge National Laboratory, Oak Ridge, TN 37831.ORCID 0000-0001-8534-1979
Maxim O LavrentovichDepartment of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996.ORCID 0000-0002-5125-7979
Jaan MännikDepartment of Physics and Astronomy, University of Tennessee, Knoxville, TN 37996.ORCID 0000-0002-6759-3053

Funding

Coordination mechanisms between cell division and chromosome segregation in E. coliR01GM127413 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI Jaan Mannik · 2018 to 2026
$2.5M
HHS | NIH (NIH) GM127413NIGMS NIH HHS R01 GM127413NSF (NSF) MCB2313719
6 · The paper itself

Abstract

The mechanisms by which two sister chromosomes separate and partition into daughter cells in bacteria remain poorly understood. A recent theoretical model has proposed that out-of-equilibrium central dogma reactions involving mRNA and ribosomes play a significant role in this process. Here, we test this idea in the

Indexed as

Chromosomes, BacterialChromosome SegregationEscherichia coliRibosomesRNA, MessengerMicroscopy, FluorescenceRNA, Messengercentral dogma processesDNA partitioningnucleoidreaction–diffusion systemsub-cellular organization

Identifiers

PMID41196350
PMCPMC12625986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.