ReviewClinical neuroradiology2026
A Child with Epileptic Seizure: A Case of Significantly Enhanced MVNT.
Review in Clinical neuroradiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis case report aims to describe an unusual presentation of multinodular and vacuolating neuronal tumor (MVNT) in a pediatric patient, highlighting its atypical radiological and clinical features.
methodsWe present the case of an 8-year-old boy with a 7-month history of seizures that progressed to daily episodes. Diagnostic workup included electroencephalography (EEG) and magnetic resonance imaging (MRI) with contrast. The lesion was resected surgically, and the diagnosis was confirmed histopathologically and immunohistochemically.
resultsEEG revealed ictal discharges in the left central, parietal, and mid-posterior temporal regions. MRI showed a left frontal cortical lesion with T1 hypointensity, T2/FLAIR hyperintensity, and unusual marked contrast enhancement, mimicking ganglioglioma. Histopathological examination confirmed MVNT. Postoperatively, the patient experienced mild left limb weakness but remained seizure-free at one-month follow-up.
conclusionThis case illustrates that MVNT can rarely occur in children and may exhibit prominent contrast enhancement and a ganglioglioma-like imaging appearance, posing a diagnostic challenge. Neurosurgeons and neuroradiologists should consider MVNT in the differential diagnosis of enhancing cortical lesions in pediatric epilepsy patients. Histopathological verification remains essential for definitive diagnosis.
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