Evidence map›Paper›PMID 41196313›Full record

ArticlePediatric cardiology2026

Hemoglobin A1c Screening Practices and Characteristics in Youth with Congenital Heart Disease.

Jonathan A Wheeler, Phillip S Cheng, Chance Alvarado, Leena Mamilly, Aaron Walsh, Kan N Hor, Andrew H Tran

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan A WheelerDivision of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, USA.
Phillip S ChengDepartment of Pediatrics, The Ohio State University, Columbus, OH, USA.
Chance AlvaradoThe Heart Center, Nationwide Children's Hospital, 700 Childrens Drive, Columbus, OH, 43205, USA.
Leena MamillySection of Endocrinology, Department of Pediatrics, Nationwide Children's Hospital/The Ohio State University College of Medicine, Columbus, OH, USA.
Aaron WalshThe Heart Institute, Le Bonheur Children's Hospital, Memphis, TN, USA.
Kan N Hor *Department of Pediatrics, The Ohio State University, Columbus, OH, USA.
Andrew H Tran *Department of Pediatrics, The Ohio State University, Columbus, OH, USA. Andrew.Tran@nationwidechildrens.org.ORCID http://orcid.org/0000-0001-5777-4611

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric congenital heart disease (CHD) patients have increased risk for cardiovascular (CV) disease. Acquired conditions such as elevated Hemoglobin A1c (HbA1c) are known risk factors for adverse CV outcomes in the adult population. With the increasing rates of pediatric prediabetes and diabetes, data are limited on the screening practices for HbA1c in children with CHD. Presence of elevated HbA1c in this population would potentially increase future CV risk. Our study aimed to evaluate screening practices for HbA1c in youth with CHD and the characteristics of those screened. Youth with CHD with primary cardiology encounters from 2012 to 2019 were evaluated. Available anthropometric, demographic, and lab data were analyzed to determine rates of HbA1c screening, screening eligibility, and compare those screened with HbA1c versus those unscreened. Of 2764 total patients, 7.9% (219/2764) had HbA1c labs with 21.9% (48/219) in the prediabetic/diabetic range. Screened patients had a higher proportion of individuals with elevated or hypertensive blood pressure measurements and overweight/obese body mass index versus unscreened patients. Although 213 patients (7.7%) were screen-eligible for HbA1c per American Diabetes Association recommendations, only 27.2% (58/213) were screened with 37.9% (22/58) in the prediabetic/diabetic range. Only a small percentage of screen-eligible patients were screened with HbA1c. Of those screened, a sizable proportion of patients were in the prediabetic/diabetic range. Improved screening practices for HbA1c and metabolic syndrome in children with CHD are needed.

Indexed as

Diabetes MellitusGlycated HemoglobinHeart Defects, CongenitalMass ScreeningPrediabetic StateAdolescentChildFemaleHumansMaleRetrospective StudiesRisk FactorsGlycated Hemoglobinhemoglobin A1c protein, humanChildrenDiabetes mellitusHemoglobin A1cMetabolic syndromePediatric cardiologyPreventive cardiology

Identifiers

PMID41196313
PMCPMC13597541

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.