ArticlePediatric cardiology2026
Left Atrial Stiffness Identifies Children with Magnetic-Resonance-Imaging-Proven Acute Myocarditis Despite Preserved Left Ventricular Systolic Function.
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The left atrium (LA) may be labeled as a "forgotten" chamber in echocardiographic evaluation of pediatric myocarditis. We recently demonstrated that LA stiffness can identify both diastolic dysfunction and myocardial injury in children with COVID-19. We sought to investigate whether LA stiffness is abnormal in children with acute myocarditis and preserved ejection fraction. We retrospectively analyzed 51 pediatric patients with acute myocarditis diagnosed by cardiac MRI based on updated Lake-Louise-Criteria, along with 40 age-matched healthy controls. Only patients with preserved LVEF (> 55%) were included, given their increased risk of adverse outcomes due to diastolic impairment. Follow-up imaging was available for 41 of the 51 patients. LV systolic and diastolic function, and LA strain were evaluated by conventional 2D and speckle-tracking echocardiography. LA stiffness was calculated as the ratio of E/e' to peak LA strain as depicted in following equation: [Formula: see text] (%
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