ArticlePediatric cardiology2026
Left Atrial Strain and History of Life-Threatening Arrhythmia in Adults with Repaired Tetralogy of Fallot: A Cardiovascular Magnetic Resonance Study.
Article in Pediatric cardiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Risk stratification for ventricular arrhythmia in adults with repaired tetralogy of Fallot (r-ToF) remains suboptimal. We investigated the relationships between left atrial reservoir strain (LAS) measured by cardiovascular magnetic resonance (CMR) and history of life-threatening ventricular arrhythmia (h-LTA) in r-ToF. We retrospectively analyzed 39 adults with r-ToF (mean age 39 ± 15 years; 69% male) undergoing routine CMR. LAS was quantified from four-chamber cine images. Patients with h-LTA, defined as a documented episode of any ventricular tachyarrhythmia, namely non-sustained ventricular tachycardia (≥ 3 consecutive ventricular beats for ≤ 30 s duration), sustained ventricular tachycardia (lasting ≥ 30 s), or ventricular fibrillation, were compared with those without. Ten patients (26%) had h-LTA. They tended to be older (46 ± 17 vs. 39 ± 13 years; p = 0.06), had longer QRS duration (167 ± 19 vs. 142 ± 25 ms; p < 0.001), and more often prior pulmonary valve replacement (40% vs. 24%; p = 0.03). LAS was significantly lower in the h-LTA group (12.9 ± 4.0% vs. 17.9 ± 4.6%; p = 0.01), while other ventricular and atrial indices, as well as late gadolinium enhancement, showed no difference. LAS correlated inversely with QRS duration (r = - 0.43; p = 0.005) and showed the strongest association with h-LTA (AUC = 0.838). Reproducibility for LAS was good (ICC = 0.84-0.97). In our study, CMR-derived LAS was markedly reduced in r-ToF patients with h-LTA. LAS demonstrated better discriminative performance in identifying patients with h-LTA. LAS may be a promising marker for arrhythmic risk stratification in r-ToF, complementing established CMR criteria, and warrants validation in larger prospective studies.
Indexed as
Identifiers
41196311What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.