Evidence map›Paper›PMID 41196301›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2026

Fracture trends in Denmark from 1997 to 2021.

Vincent P Visker, Annika Vestergaard Kvist, Peter Vestergaard, Joop P van den Bergh, Martijn C J G Brouwers, Caroline E Wyers, Johanna H M Driessen

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Vincent P Visker *Department of Clinical Pharmacy and Toxicology, Maastricht University Medical Center+ (MUMC+), PO Box 5800, Maastricht, 6202 AZ, the Netherlands.
Annika Vestergaard Kvist *Steno Diabetes Center North Denmark, Aalborg Universitetshospital, Hospitalsbyen 2-4, Aalborg, Gistrup, 9260, Denmark.
Peter VestergaardSteno Diabetes Center North Denmark, Aalborg Universitetshospital, Hospitalsbyen 2-4, Aalborg, Gistrup, 9260, Denmark.
Joop P van den BerghSchool of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.
Martijn C J G BrouwersDepartment of Internal Medicine, Maastricht University Medical Center+ (MUMC+), Maastricht, the Netherlands.
Caroline E WyersSchool of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University, Maastricht, the Netherlands.
Johanna H M DriessenDepartment of Clinical Pharmacy and Toxicology, Maastricht University Medical Center+ (MUMC+), PO Box 5800, Maastricht, 6202 AZ, the Netherlands. annemariek.driessen@mumc.nl.ORCID http://orcid.org/0000-0002-4503-6408

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated fracture trends in adults in Denmark between 1997 and 2021. Major osteoporotic fracture incidence rates (IRs) decreased in both women and men. Hip fracture IRs decreased in women and men. However, there was an increase in vertebral fracture IRs which should be further investigated. PURPOSE: As population characteristics change over time, fracture incidence rates are likely to change as well. However, to date, no studies have reported the trends in sex- and fracture site-specific IRs using recent data from Denmark. Our aim was to investigate changes in fracture IRs in Denmark between 1997 and 2021.

methodsWe identified adults with a fracture in 1997-2021 in the Danish National Patient Register. Annual age-standardized fracture IRs per 10,000 person-years (PY) with 95% confidence intervals were calculated. Poisson regression was used to test the significance of changes over time in fracture IRs.

resultsWe identified 1,478,808 individuals with fractures. The population had a median age of 55 years and consisted of 54% women. Major osteoporotic fracture IRs in women decreased from 135.8 to 116.9 per 10,000 PY from 1997 to 2021, and decreased in men from 62.3 to 57.2 per 10,000 PY. Hip fracture IRs decreased from 41.5 in 1997 to 23.3 in 2021 for women and from 19.6 to 13.3 for men. Vertebral fracture IRs increased from 8.6 and 7.8 in 1997, to 15.2 and 11.9 in 2021 for women and men respectively. Humerus and forearm fracture IRs decreased slightly in women and men.

conclusionsBetween 1997 and 2021 hip fracture IRs decreased, while vertebral fracture IRs increased. The increased vertebral fracture IRs might be attributed to an increased detection rate. Although major osteoporotic fracture IRs decreased more in women than in men, women still have higher IRs of hip, humerus, and forearm fractures than men.

Indexed as

Osteoporotic FracturesAdultAgedAged, 80 and overAge DistributionDenmarkFemaleForearm InjuriesHip FracturesHumansIncidenceMaleMiddle AgedRegistriesSex DistributionSpinal FracturesEpidemiologyFractureIncidence ratesOsteoporosisSecular trends

Identifiers

PMID41196301

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.